Serological CTX-II does not measure the same as urinary CTX-II

Summary: Objective: Type II collagen is the most abundant protein of articular cartilage. The urinary cross-linked C-terminal telopeptide of type II collagen (uCTX-II) is a matrix metalloproteinase (MMP) cleaved fragment and may be the most well-validated biomarker in osteoarthritis. The aim was to...

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Bibliographic Details
Main Authors: Yunyun Luo, Yi He, Morten Karsdal, Anne-Christine Bay-Jensen
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Osteoarthritis and Cartilage Open
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S266591312030073X