Characterization and Function of MicroRNA∗s in Plants
MicroRNAs, a group of non-coding RNA molecules, play essential roles in a wide range of cellular processes in different molecules, cells, and organisms. In plants, microRNAs are a class of 20- to 24-nucleotides endogenous small RNAs that repress gene expression. The microRNA guide strand (miRNA) and...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2017-12-01
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| Series: | Frontiers in Plant Science |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/article/10.3389/fpls.2017.02200/full |
| _version_ | 1818519759696691200 |
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| author | Wei-wei Liu Jun Meng Jun Cui Yu-shi Luan |
| author_facet | Wei-wei Liu Jun Meng Jun Cui Yu-shi Luan |
| author_sort | Wei-wei Liu |
| collection | DOAJ |
| description | MicroRNAs, a group of non-coding RNA molecules, play essential roles in a wide range of cellular processes in different molecules, cells, and organisms. In plants, microRNAs are a class of 20- to 24-nucleotides endogenous small RNAs that repress gene expression. The microRNA guide strand (miRNA) and its complementary strand (miRNA∗) both originate from the miRNA/miRNA∗ duplex. Generally, the guide strands act as post-transcriptional regulators that suppress gene expression by cleaving their target mRNA transcripts, whereas the complementary strands were thought to be degraded as ‘passenger strands.’ However, the complementary strand has been confirmed to possess significant biological functionality in recent reports. In this review, we summarized the binding characteristics of the miRNA∗ strands with ARGONAUTE proteins, their tissue-specific accumulations and their biological functions, illustrating the essential roles of miRNA∗s in biological processes and therefore providing directions for further exploration. |
| first_indexed | 2024-12-11T01:28:21Z |
| format | Article |
| id | doaj.art-b4a5cfcb444b4093af147559b8c8fe03 |
| institution | Directory Open Access Journal |
| issn | 1664-462X |
| language | English |
| last_indexed | 2024-12-11T01:28:21Z |
| publishDate | 2017-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Plant Science |
| spelling | doaj.art-b4a5cfcb444b4093af147559b8c8fe032022-12-22T01:25:27ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2017-12-01810.3389/fpls.2017.02200319830Characterization and Function of MicroRNA∗s in PlantsWei-wei Liu0Jun Meng1Jun Cui2Yu-shi Luan3School of Life Sciences and Biotechnology, Dalian University of Technology, Dalian, ChinaSchool of Computer Science and Technology, Dalian University of Technology, Dalian, ChinaSchool of Life Sciences and Biotechnology, Dalian University of Technology, Dalian, ChinaSchool of Life Sciences and Biotechnology, Dalian University of Technology, Dalian, ChinaMicroRNAs, a group of non-coding RNA molecules, play essential roles in a wide range of cellular processes in different molecules, cells, and organisms. In plants, microRNAs are a class of 20- to 24-nucleotides endogenous small RNAs that repress gene expression. The microRNA guide strand (miRNA) and its complementary strand (miRNA∗) both originate from the miRNA/miRNA∗ duplex. Generally, the guide strands act as post-transcriptional regulators that suppress gene expression by cleaving their target mRNA transcripts, whereas the complementary strands were thought to be degraded as ‘passenger strands.’ However, the complementary strand has been confirmed to possess significant biological functionality in recent reports. In this review, we summarized the binding characteristics of the miRNA∗ strands with ARGONAUTE proteins, their tissue-specific accumulations and their biological functions, illustrating the essential roles of miRNA∗s in biological processes and therefore providing directions for further exploration.http://journal.frontiersin.org/article/10.3389/fpls.2017.02200/fullmiRNAmiRNA∗passenger strandARGONAUTE proteinstress response |
| spellingShingle | Wei-wei Liu Jun Meng Jun Cui Yu-shi Luan Characterization and Function of MicroRNA∗s in Plants Frontiers in Plant Science miRNA miRNA∗ passenger strand ARGONAUTE protein stress response |
| title | Characterization and Function of MicroRNA∗s in Plants |
| title_full | Characterization and Function of MicroRNA∗s in Plants |
| title_fullStr | Characterization and Function of MicroRNA∗s in Plants |
| title_full_unstemmed | Characterization and Function of MicroRNA∗s in Plants |
| title_short | Characterization and Function of MicroRNA∗s in Plants |
| title_sort | characterization and function of microrna∗s in plants |
| topic | miRNA miRNA∗ passenger strand ARGONAUTE protein stress response |
| url | http://journal.frontiersin.org/article/10.3389/fpls.2017.02200/full |
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