Duplex DNA-Invading γ-Modified Peptide Nucleic Acids Enable Rapid Identification of Bloodstream Infections in Whole Blood

Duplex DNA-Invading γ-Modified Peptide Nucleic Acids Enable Rapid Identification of Bloodstream Infections in Whole Blood

ABSTRACT Bloodstream infections are a leading cause of morbidity and mortality. Early and targeted antimicrobial intervention is lifesaving, yet current diagnostic approaches fail to provide actionable information within a clinically viable time frame due to their reliance on blood culturing. Here,...

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Bibliographic Details
Main Authors: Jörk Nölling, Srinivas Rapireddy, Joel I. Amburg, Elizabeth M. Crawford, Ranjit A. Prakash, Arthur R. Rabson, Yi-Wei Tang, Alon Singer
Format: Article
Language:English
Published: American Society for Microbiology 2016-05-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00345-16

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