Predicting response to combination evofosfamide and immunotherapy under hypoxic conditions in murine models of colon cancer
The goal of this study is to develop a mathematical model that captures the interaction between evofosfamide, immunotherapy, and the hypoxic landscape of the tumor in the treatment of tumors. Recently, we showed that evofosfamide, a hypoxia-activated prodrug, can synergistically improve treatment ou...
Main Authors: | Ernesto A. B. F. Lima, Patrick N. Song, Kirsten Reeves, Benjamin Larimer, Anna G. Sorace, Thomas E. Yankeelov |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2023-09-01
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Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2023783?viewType=HTML |
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