Post-COVID-19 syndrome symptoms after mild and moderate SARS-CoV-2 infection
BackgroundPost-COVID-19 Syndrome (PCS) is characterized by residual symptoms following the initial recovery from severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. The prevalence of PCS is known to be the highest among severe and critical forms of the disease. However, the occur...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-10-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2022.1017257/full |
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| author | Lou’i Al-Husinat Mokeem Nusir Haitham Al-Gharaibeh Amer A. Alomari Mahmoud M. Smadi Denise Battaglini Paolo Pelosi Paolo Pelosi |
| author_facet | Lou’i Al-Husinat Mokeem Nusir Haitham Al-Gharaibeh Amer A. Alomari Mahmoud M. Smadi Denise Battaglini Paolo Pelosi Paolo Pelosi |
| author_sort | Lou’i Al-Husinat |
| collection | DOAJ |
| description | BackgroundPost-COVID-19 Syndrome (PCS) is characterized by residual symptoms following the initial recovery from severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. The prevalence of PCS is known to be the highest among severe and critical forms of the disease. However, the occurrence and risk factors for PCS after mild or moderate SARS-CoV-2 infection has not been extensively investigated.MethodsOnline and offline via both paper or mailed questionnaires distributed among Jordan collected between 1st and 21st August 2021, including a total number of 800 respondents, of whom 495 had previous mild to moderate COVID-19 infection. The Newcastle post-COVID syndrome Follow-up Screening Questionnaire was modified, translated, and used as a standard instrument for data collection regarding psychological, medical, and socio-economic symptoms post-infection. The primary outcome was the prevalence of PCS after mild to moderate COVID-19 in Jordan. Secondary outcome was the identification of PCS risk factors.ResultsThe most common PCS symptom was mood disturbance followed by fatigue, anxiety, and myalgia. Female gender significantly increased the risk for multiple PCS symptoms. Age < 30 years was found to be an independent risk factor for myalgia (p = 0.001).ConclusionPCS is highly prevalent among COVID-19 survivors in Jordan, especially in females and patients with comorbidities. Planning physical and mental rehabilitation services is recommended for those patients with PCS symptoms after mild to moderate COVID-19 infection. |
| first_indexed | 2024-04-12T10:21:48Z |
| format | Article |
| id | doaj.art-b4a7903acf964a4198d56115bb0fb94c |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-04-12T10:21:48Z |
| publishDate | 2022-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-b4a7903acf964a4198d56115bb0fb94c2022-12-22T03:37:04ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2022-10-01910.3389/fmed.2022.10172571017257Post-COVID-19 syndrome symptoms after mild and moderate SARS-CoV-2 infectionLou’i Al-Husinat0Mokeem Nusir1Haitham Al-Gharaibeh2Amer A. Alomari3Mahmoud M. Smadi4Denise Battaglini5Paolo Pelosi6Paolo Pelosi7Department of Clinical Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid, JordanDepartment of Clinical Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid, JordanDepartment of Clinical Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid, JordanDepartment of Neurosurgery, San Filippo Neri Hospital/ASLRoma1, Rome, ItalyDepartment of Mathematics and Statistics, Jordan University of Science and Technology, Irbid, JordanAnesthesia and Intensive Care, San Martino Policlinico Hospital, IRCCS for Oncology and Neuroscience, Genoa, ItalyAnesthesia and Intensive Care, San Martino Policlinico Hospital, IRCCS for Oncology and Neuroscience, Genoa, ItalyDepartment of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, ItalyBackgroundPost-COVID-19 Syndrome (PCS) is characterized by residual symptoms following the initial recovery from severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. The prevalence of PCS is known to be the highest among severe and critical forms of the disease. However, the occurrence and risk factors for PCS after mild or moderate SARS-CoV-2 infection has not been extensively investigated.MethodsOnline and offline via both paper or mailed questionnaires distributed among Jordan collected between 1st and 21st August 2021, including a total number of 800 respondents, of whom 495 had previous mild to moderate COVID-19 infection. The Newcastle post-COVID syndrome Follow-up Screening Questionnaire was modified, translated, and used as a standard instrument for data collection regarding psychological, medical, and socio-economic symptoms post-infection. The primary outcome was the prevalence of PCS after mild to moderate COVID-19 in Jordan. Secondary outcome was the identification of PCS risk factors.ResultsThe most common PCS symptom was mood disturbance followed by fatigue, anxiety, and myalgia. Female gender significantly increased the risk for multiple PCS symptoms. Age < 30 years was found to be an independent risk factor for myalgia (p = 0.001).ConclusionPCS is highly prevalent among COVID-19 survivors in Jordan, especially in females and patients with comorbidities. Planning physical and mental rehabilitation services is recommended for those patients with PCS symptoms after mild to moderate COVID-19 infection.https://www.frontiersin.org/articles/10.3389/fmed.2022.1017257/fullpost-COVID-19 syndromeSARS-CoV-2 infectionchronic COVID-19 syndromemood disturbancepost-acute sequelae of SARS-CoV-2 infection |
| spellingShingle | Lou’i Al-Husinat Mokeem Nusir Haitham Al-Gharaibeh Amer A. Alomari Mahmoud M. Smadi Denise Battaglini Paolo Pelosi Paolo Pelosi Post-COVID-19 syndrome symptoms after mild and moderate SARS-CoV-2 infection Frontiers in Medicine post-COVID-19 syndrome SARS-CoV-2 infection chronic COVID-19 syndrome mood disturbance post-acute sequelae of SARS-CoV-2 infection |
| title | Post-COVID-19 syndrome symptoms after mild and moderate SARS-CoV-2 infection |
| title_full | Post-COVID-19 syndrome symptoms after mild and moderate SARS-CoV-2 infection |
| title_fullStr | Post-COVID-19 syndrome symptoms after mild and moderate SARS-CoV-2 infection |
| title_full_unstemmed | Post-COVID-19 syndrome symptoms after mild and moderate SARS-CoV-2 infection |
| title_short | Post-COVID-19 syndrome symptoms after mild and moderate SARS-CoV-2 infection |
| title_sort | post covid 19 syndrome symptoms after mild and moderate sars cov 2 infection |
| topic | post-COVID-19 syndrome SARS-CoV-2 infection chronic COVID-19 syndrome mood disturbance post-acute sequelae of SARS-CoV-2 infection |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2022.1017257/full |
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