The impact of COVID-19 certification mandates on the number of cases of and hospitalizations with COVID-19 in the UK: A difference-in-differences analysis

BackgroundMandatory COVID-19 certification, showing proof of vaccination, negative test, or recent infection to access to public venues, was introduced at different times in the four countries of the UK. We aim to study its effects on the incidence of cases and hospital admissions.MethodsWe performe...

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Main Authors: Kim López-Güell, Albert Prats-Uribe, Martí Català, Clara Prats, Jotun Hein, Daniel Prieto-Alhambra
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Public Health
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2023.1019223/full
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author Kim López-Güell
Albert Prats-Uribe
Martí Català
Clara Prats
Jotun Hein
Daniel Prieto-Alhambra
author_facet Kim López-Güell
Albert Prats-Uribe
Martí Català
Clara Prats
Jotun Hein
Daniel Prieto-Alhambra
author_sort Kim López-Güell
collection DOAJ
description BackgroundMandatory COVID-19 certification, showing proof of vaccination, negative test, or recent infection to access to public venues, was introduced at different times in the four countries of the UK. We aim to study its effects on the incidence of cases and hospital admissions.MethodsWe performed Negative binomial segmented regression and ARIMA analyses for four countries (England, Northern Ireland, Scotland and Wales), and fitted Difference-in-Differences models to compare the latter three to England, as a negative control group, since it was the last country where COVID-19 certification was introduced. The main outcome was the weekly averaged incidence of COVID-19 cases and hospital admissions.ResultsCOVID-19 certification led to a decrease in the incidence of cases and hospital admissions in Northern Ireland, as well as in Wales during the second half of November. The same was seen for hospital admissions in Wales and Scotland during October. In Wales the incidence rate of cases in October already had a decreasing tendency, as well as in England, hence a particular impact of COVID-19 certification was less obvious. Method assumptions for the Difference-in-Differences analysis did not hold for Scotland. Additional NBSR and ARIMA models suggest similar results, while also accounting for correlation in the latter. The assessment of the effect in England itself leads one to believe that this intervention might not be strong enough for the Omicron variant, which was prevalent at the time of introduction of COVID-19 certification in the country.ConclusionsMandatory COVID-19 certification reduced COVID-19 transmission and hospitalizations when Delta predominated in the UK, but lost efficacy when Omicron became the most common variant.
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spelling doaj.art-b4a8105f3d5045249a35645264e439df2023-02-24T05:24:04ZengFrontiers Media S.A.Frontiers in Public Health2296-25652023-02-011110.3389/fpubh.2023.10192231019223The impact of COVID-19 certification mandates on the number of cases of and hospitalizations with COVID-19 in the UK: A difference-in-differences analysisKim López-Güell0Albert Prats-Uribe1Martí Català2Clara Prats3Jotun Hein4Daniel Prieto-Alhambra5Department of Statistics, University of Oxford, Oxford, United KingdomCentre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, United KingdomCentre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, United KingdomEscola Superior d'Agricultura de Barcelona, Campus del Baix Llobregat, Departament de Física i Enginyeria Nuclear, Universitat Politècnica de Catalunya, Barcelona, SpainDepartment of Statistics, University of Oxford, Oxford, United KingdomCentre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, United KingdomBackgroundMandatory COVID-19 certification, showing proof of vaccination, negative test, or recent infection to access to public venues, was introduced at different times in the four countries of the UK. We aim to study its effects on the incidence of cases and hospital admissions.MethodsWe performed Negative binomial segmented regression and ARIMA analyses for four countries (England, Northern Ireland, Scotland and Wales), and fitted Difference-in-Differences models to compare the latter three to England, as a negative control group, since it was the last country where COVID-19 certification was introduced. The main outcome was the weekly averaged incidence of COVID-19 cases and hospital admissions.ResultsCOVID-19 certification led to a decrease in the incidence of cases and hospital admissions in Northern Ireland, as well as in Wales during the second half of November. The same was seen for hospital admissions in Wales and Scotland during October. In Wales the incidence rate of cases in October already had a decreasing tendency, as well as in England, hence a particular impact of COVID-19 certification was less obvious. Method assumptions for the Difference-in-Differences analysis did not hold for Scotland. Additional NBSR and ARIMA models suggest similar results, while also accounting for correlation in the latter. The assessment of the effect in England itself leads one to believe that this intervention might not be strong enough for the Omicron variant, which was prevalent at the time of introduction of COVID-19 certification in the country.ConclusionsMandatory COVID-19 certification reduced COVID-19 transmission and hospitalizations when Delta predominated in the UK, but lost efficacy when Omicron became the most common variant.https://www.frontiersin.org/articles/10.3389/fpubh.2023.1019223/fullcovid certificatecovid passportreal-world dataobservational studiespublic health
spellingShingle Kim López-Güell
Albert Prats-Uribe
Martí Català
Clara Prats
Jotun Hein
Daniel Prieto-Alhambra
The impact of COVID-19 certification mandates on the number of cases of and hospitalizations with COVID-19 in the UK: A difference-in-differences analysis
Frontiers in Public Health
covid certificate
covid passport
real-world data
observational studies
public health
title The impact of COVID-19 certification mandates on the number of cases of and hospitalizations with COVID-19 in the UK: A difference-in-differences analysis
title_full The impact of COVID-19 certification mandates on the number of cases of and hospitalizations with COVID-19 in the UK: A difference-in-differences analysis
title_fullStr The impact of COVID-19 certification mandates on the number of cases of and hospitalizations with COVID-19 in the UK: A difference-in-differences analysis
title_full_unstemmed The impact of COVID-19 certification mandates on the number of cases of and hospitalizations with COVID-19 in the UK: A difference-in-differences analysis
title_short The impact of COVID-19 certification mandates on the number of cases of and hospitalizations with COVID-19 in the UK: A difference-in-differences analysis
title_sort impact of covid 19 certification mandates on the number of cases of and hospitalizations with covid 19 in the uk a difference in differences analysis
topic covid certificate
covid passport
real-world data
observational studies
public health
url https://www.frontiersin.org/articles/10.3389/fpubh.2023.1019223/full
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