Gastric transcatheter chemoembolization can resolve advanced gastric cancer presenting with obstruction
BackgroundGastric transcatheter chemoembolization (GTC) is an interventional minimal invasive method, which has never been mentioned in the previous literature for advanced gastric cancer with obstruction. The purpose of this study was to evaluate its safety and efficacy in treating advanced gastric...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-10-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2022.1004064/full |
| _version_ | 1811340187442085888 |
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| author | Dong Peng Bin Zhang Chao Yuan Yue Tong Wei Zhang |
| author_facet | Dong Peng Bin Zhang Chao Yuan Yue Tong Wei Zhang |
| author_sort | Dong Peng |
| collection | DOAJ |
| description | BackgroundGastric transcatheter chemoembolization (GTC) is an interventional minimal invasive method, which has never been mentioned in the previous literature for advanced gastric cancer with obstruction. The purpose of this study was to evaluate its safety and efficacy in treating advanced gastric cancer with obstruction.MethodsAdvanced gastric cancer patients with obstruction who underwent GTC were retrospectively analysed from June 2017 to January 2020. Baseline information, peri-intervention data, and post-intervention follow-up information were collected. Clinical data obtained before and after the GTC were compared, and the survival of all patients was analysed.ResultForty-Two patients were included in this study. 42 (100%) patients achieved technical success, and 22 (52.4%) achieved clinical success. The median time of the GTC was 83 (30.0–180.0) minutes, and the median time of hospitalization after GTC was 3 (1–6) days. One patient experienced abdominal pain during and after GTC. Twenty (47.6%) of the 42 patients underwent gastrectomy after intervention. The pre-intervention gastric outlet obstruction scoring system (GOOSS) was 1 (0–1) and the post-intervention GOOSS was 2 (0–3) (p = 0.000 < 0.05). The median follow-up time was 9.5 (3–35) months, and the overall survival time was 14 months. In the univariate survival analysis, a significant difference was observed between patients who did or did not undergo radical gastrectomy after GTC (p = 0.014 < 0.05).ConclusionsGTC is a safe and effective treatment, and furthermore, it could be an alternative method in treating advanced gastric cancer with obstruction. |
| first_indexed | 2024-04-13T18:37:21Z |
| format | Article |
| id | doaj.art-b4adc23e42b94aafbf3bec2a9c2f8220 |
| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-04-13T18:37:21Z |
| publishDate | 2022-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Surgery |
| spelling | doaj.art-b4adc23e42b94aafbf3bec2a9c2f82202022-12-22T02:34:50ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2022-10-01910.3389/fsurg.2022.10040641004064Gastric transcatheter chemoembolization can resolve advanced gastric cancer presenting with obstructionDong PengBin ZhangChao YuanYue TongWei ZhangBackgroundGastric transcatheter chemoembolization (GTC) is an interventional minimal invasive method, which has never been mentioned in the previous literature for advanced gastric cancer with obstruction. The purpose of this study was to evaluate its safety and efficacy in treating advanced gastric cancer with obstruction.MethodsAdvanced gastric cancer patients with obstruction who underwent GTC were retrospectively analysed from June 2017 to January 2020. Baseline information, peri-intervention data, and post-intervention follow-up information were collected. Clinical data obtained before and after the GTC were compared, and the survival of all patients was analysed.ResultForty-Two patients were included in this study. 42 (100%) patients achieved technical success, and 22 (52.4%) achieved clinical success. The median time of the GTC was 83 (30.0–180.0) minutes, and the median time of hospitalization after GTC was 3 (1–6) days. One patient experienced abdominal pain during and after GTC. Twenty (47.6%) of the 42 patients underwent gastrectomy after intervention. The pre-intervention gastric outlet obstruction scoring system (GOOSS) was 1 (0–1) and the post-intervention GOOSS was 2 (0–3) (p = 0.000 < 0.05). The median follow-up time was 9.5 (3–35) months, and the overall survival time was 14 months. In the univariate survival analysis, a significant difference was observed between patients who did or did not undergo radical gastrectomy after GTC (p = 0.014 < 0.05).ConclusionsGTC is a safe and effective treatment, and furthermore, it could be an alternative method in treating advanced gastric cancer with obstruction.https://www.frontiersin.org/articles/10.3389/fsurg.2022.1004064/fullgastric cancerobstructiongastric transcatheter chemoembolizationoutcomesurvival |
| spellingShingle | Dong Peng Bin Zhang Chao Yuan Yue Tong Wei Zhang Gastric transcatheter chemoembolization can resolve advanced gastric cancer presenting with obstruction Frontiers in Surgery gastric cancer obstruction gastric transcatheter chemoembolization outcome survival |
| title | Gastric transcatheter chemoembolization can resolve advanced gastric cancer presenting with obstruction |
| title_full | Gastric transcatheter chemoembolization can resolve advanced gastric cancer presenting with obstruction |
| title_fullStr | Gastric transcatheter chemoembolization can resolve advanced gastric cancer presenting with obstruction |
| title_full_unstemmed | Gastric transcatheter chemoembolization can resolve advanced gastric cancer presenting with obstruction |
| title_short | Gastric transcatheter chemoembolization can resolve advanced gastric cancer presenting with obstruction |
| title_sort | gastric transcatheter chemoembolization can resolve advanced gastric cancer presenting with obstruction |
| topic | gastric cancer obstruction gastric transcatheter chemoembolization outcome survival |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2022.1004064/full |
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