Hypertension in COVID-19, A Risk Factor for Infection or A Late Consequence?
There are a lot of data about the correlation of SARS-CoV-2 infection and hypertension (HTN), but most of themare in the increased risk of morbidity and mortality in patients with HTN. SARS-CoV-2 can interfere with host cellsthrough the renin-angiotensin system (RAS) via the angiotensin-converting e...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Royan Institute (ACECR), Tehran
2022-07-01
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| Series: | Cell Journal |
| Subjects: | |
| Online Access: | https://www.celljournal.org/article_253309_46f71e1cd2d36d2d2d2d2099c1336eb3.pdf |
| _version_ | 1817999343118974976 |
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| author | Maryam Barekat Mohammad Amin Shahrbaf Kosar Rahi Massoud Vosough |
| author_facet | Maryam Barekat Mohammad Amin Shahrbaf Kosar Rahi Massoud Vosough |
| author_sort | Maryam Barekat |
| collection | DOAJ |
| description | There are a lot of data about the correlation of SARS-CoV-2 infection and hypertension (HTN), but most of themare in the increased risk of morbidity and mortality in patients with HTN. SARS-CoV-2 can interfere with host cellsthrough the renin-angiotensin system (RAS) via the angiotensin-converting enzyme 2 (ACE2) receptor. RAS activationis associated with pro-inflammatory effects through the ACE/Ang II/ Angiotensin II type 1 receptor (AT1R) pathwayor anti-inflammatory effects through ACE2/Ang1-7/Mas axis. In the current paper, we discuss the pathophysiology ofnewly diagnosed HTN and its effect on morbidity in patients with coronavirus disease 2019 (COVID-19). |
| first_indexed | 2024-04-14T03:07:22Z |
| format | Article |
| id | doaj.art-b4ae70eb0f36400d9aa9c182d6c17ba7 |
| institution | Directory Open Access Journal |
| issn | 2228-5806 2228-5814 |
| language | English |
| last_indexed | 2024-04-14T03:07:22Z |
| publishDate | 2022-07-01 |
| publisher | Royan Institute (ACECR), Tehran |
| record_format | Article |
| series | Cell Journal |
| spelling | doaj.art-b4ae70eb0f36400d9aa9c182d6c17ba72022-12-22T02:15:41ZengRoyan Institute (ACECR), TehranCell Journal2228-58062228-58142022-07-0124742442610.22074/cellj.2022.8487253309Hypertension in COVID-19, A Risk Factor for Infection or A Late Consequence?Maryam Barekat0Mohammad Amin Shahrbaf1Kosar Rahi2Massoud Vosough3Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, IranDepartment of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, IranDepartment of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, IranDepartment of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, IranThere are a lot of data about the correlation of SARS-CoV-2 infection and hypertension (HTN), but most of themare in the increased risk of morbidity and mortality in patients with HTN. SARS-CoV-2 can interfere with host cellsthrough the renin-angiotensin system (RAS) via the angiotensin-converting enzyme 2 (ACE2) receptor. RAS activationis associated with pro-inflammatory effects through the ACE/Ang II/ Angiotensin II type 1 receptor (AT1R) pathwayor anti-inflammatory effects through ACE2/Ang1-7/Mas axis. In the current paper, we discuss the pathophysiology ofnewly diagnosed HTN and its effect on morbidity in patients with coronavirus disease 2019 (COVID-19).https://www.celljournal.org/article_253309_46f71e1cd2d36d2d2d2d2099c1336eb3.pdfcovid-19hypertensionrenin-angiotensin-aldosterone system |
| spellingShingle | Maryam Barekat Mohammad Amin Shahrbaf Kosar Rahi Massoud Vosough Hypertension in COVID-19, A Risk Factor for Infection or A Late Consequence? Cell Journal covid-19 hypertension renin-angiotensin-aldosterone system |
| title | Hypertension in COVID-19, A Risk Factor for Infection or A Late Consequence? |
| title_full | Hypertension in COVID-19, A Risk Factor for Infection or A Late Consequence? |
| title_fullStr | Hypertension in COVID-19, A Risk Factor for Infection or A Late Consequence? |
| title_full_unstemmed | Hypertension in COVID-19, A Risk Factor for Infection or A Late Consequence? |
| title_short | Hypertension in COVID-19, A Risk Factor for Infection or A Late Consequence? |
| title_sort | hypertension in covid 19 a risk factor for infection or a late consequence |
| topic | covid-19 hypertension renin-angiotensin-aldosterone system |
| url | https://www.celljournal.org/article_253309_46f71e1cd2d36d2d2d2d2099c1336eb3.pdf |
| work_keys_str_mv | AT maryambarekat hypertensionincovid19ariskfactorforinfectionoralateconsequence AT mohammadaminshahrbaf hypertensionincovid19ariskfactorforinfectionoralateconsequence AT kosarrahi hypertensionincovid19ariskfactorforinfectionoralateconsequence AT massoudvosough hypertensionincovid19ariskfactorforinfectionoralateconsequence |