Intraocular RGD-Engineered Exosomes and Active Targeting of Choroidal Neovascularization (CNV)

Intraocular RGD-Engineered Exosomes and Active Targeting of Choroidal Neovascularization (CNV)

Purpose: To assess the transretinal penetration of intravitreally injected retinal multicell-derived exosomes and to develop exosome-based active targeting of choroidal neovascularization (CNV) by bioengineering with ASL, which is composed of a membrane Anchor (BODIPY), Spacer (PEG), and targeting L...

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Bibliographic Details
Main Authors: Dimitrios Pollalis, Dongin Kim, Gopa Kumar Gopinadhan Nair, Changsun Kang, Arjun V. Nanda, Sun Young Lee
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
active targeting
choroidal neovascularization
exosome
Online Access:https://www.mdpi.com/2073-4409/11/16/2573

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