Comparative Analysis of Anticancer and Antibacterial Activities among Seven Trametes Species
AbstractSpecies in the genus Trametes (Basidiomycota, Polyporales) have been used in natural medicine for a long time. Many studies reported that mycelia or fruiting bodies of Trametes spp. exhibited effects of antioxidant, anti-inflammatory, anticancer, and antimicrobial activities. However, compar...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-07-01
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| Series: | Mycobiology |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/12298093.2023.2247218 |
| _version_ | 1797687647815073792 |
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| author | Ha Thi Kim Nguyen Jiwon Lee Yejin Park Hyon Jin Park Soon Kil Ahn Jae Kwang Kim Dong-Ku Kang Minkyeong Kim Chorong Ahn Changmu Kim Jaehyuk Choi |
| author_facet | Ha Thi Kim Nguyen Jiwon Lee Yejin Park Hyon Jin Park Soon Kil Ahn Jae Kwang Kim Dong-Ku Kang Minkyeong Kim Chorong Ahn Changmu Kim Jaehyuk Choi |
| author_sort | Ha Thi Kim Nguyen |
| collection | DOAJ |
| description | AbstractSpecies in the genus Trametes (Basidiomycota, Polyporales) have been used in natural medicine for a long time. Many studies reported that mycelia or fruiting bodies of Trametes spp. exhibited effects of antioxidant, anti-inflammatory, anticancer, and antimicrobial activities. However, comparative analysis in this genus is scarce due to limitation of morphological identification and the sample number. In this study, the 19 strains of seven Trametes species were chosen to generate a five-gene-based phylogeny with the 31 global references. In addition, 39 culture extracts were prepared for 13 strains to test for anticancer and antibacterial activities. Strong anticancer activities were found in several extracts from T. hirsuta and T. suaveolens. Anticancer activities of T. suaveolens, T. cf. junipericola and T. trogii were first described here. The antibacterial ability of T. versicolor and T. hirsuta extracts has been confirmed. The antibacterial activities of T. suaveolens have been reported at the first time in this study. These results suggest an efficient application of the genus Trametes as the drug resources especially for anticancer agents. |
| first_indexed | 2024-03-12T01:20:46Z |
| format | Article |
| id | doaj.art-b4b211d624394721b7c6137effe6df68 |
| institution | Directory Open Access Journal |
| issn | 1229-8093 2092-9323 |
| language | English |
| last_indexed | 2024-03-12T01:20:46Z |
| publishDate | 2023-07-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Mycobiology |
| spelling | doaj.art-b4b211d624394721b7c6137effe6df682023-09-13T05:45:27ZengTaylor & Francis GroupMycobiology1229-80932092-93232023-07-0151425626310.1080/12298093.2023.2247218Comparative Analysis of Anticancer and Antibacterial Activities among Seven Trametes SpeciesHa Thi Kim Nguyen0Jiwon Lee1Yejin Park2Hyon Jin Park3Soon Kil Ahn4Jae Kwang Kim5Dong-Ku Kang6Minkyeong Kim7Chorong Ahn8Changmu Kim9Jaehyuk Choi10Division of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Incheon, KoreaDivision of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Incheon, KoreaDivision of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Incheon, KoreaDivision of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Incheon, KoreaDivision of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Incheon, KoreaDivision of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Incheon, KoreaDepartment of Chemistry, College of Natural Sciences, Incheon National University, Incheon, KoreaSpecies Diversity Research Division, National Institute of Biological Resources, Incheon, KoreaSpecies Diversity Research Division, National Institute of Biological Resources, Incheon, KoreaSpecies Diversity Research Division, National Institute of Biological Resources, Incheon, KoreaDivision of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Incheon, KoreaAbstractSpecies in the genus Trametes (Basidiomycota, Polyporales) have been used in natural medicine for a long time. Many studies reported that mycelia or fruiting bodies of Trametes spp. exhibited effects of antioxidant, anti-inflammatory, anticancer, and antimicrobial activities. However, comparative analysis in this genus is scarce due to limitation of morphological identification and the sample number. In this study, the 19 strains of seven Trametes species were chosen to generate a five-gene-based phylogeny with the 31 global references. In addition, 39 culture extracts were prepared for 13 strains to test for anticancer and antibacterial activities. Strong anticancer activities were found in several extracts from T. hirsuta and T. suaveolens. Anticancer activities of T. suaveolens, T. cf. junipericola and T. trogii were first described here. The antibacterial ability of T. versicolor and T. hirsuta extracts has been confirmed. The antibacterial activities of T. suaveolens have been reported at the first time in this study. These results suggest an efficient application of the genus Trametes as the drug resources especially for anticancer agents.https://www.tandfonline.com/doi/10.1080/12298093.2023.2247218Trametesanticancerantibacterialantitumorantimicrobial |
| spellingShingle | Ha Thi Kim Nguyen Jiwon Lee Yejin Park Hyon Jin Park Soon Kil Ahn Jae Kwang Kim Dong-Ku Kang Minkyeong Kim Chorong Ahn Changmu Kim Jaehyuk Choi Comparative Analysis of Anticancer and Antibacterial Activities among Seven Trametes Species Mycobiology Trametes anticancer antibacterial antitumor antimicrobial |
| title | Comparative Analysis of Anticancer and Antibacterial Activities among Seven Trametes Species |
| title_full | Comparative Analysis of Anticancer and Antibacterial Activities among Seven Trametes Species |
| title_fullStr | Comparative Analysis of Anticancer and Antibacterial Activities among Seven Trametes Species |
| title_full_unstemmed | Comparative Analysis of Anticancer and Antibacterial Activities among Seven Trametes Species |
| title_short | Comparative Analysis of Anticancer and Antibacterial Activities among Seven Trametes Species |
| title_sort | comparative analysis of anticancer and antibacterial activities among seven trametes species |
| topic | Trametes anticancer antibacterial antitumor antimicrobial |
| url | https://www.tandfonline.com/doi/10.1080/12298093.2023.2247218 |
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