Signature-tagged mutagenesis in a chicken infection model leads to the identification of a novel avian pathogenic Escherichia coli fimbrial adhesin.
The extraintestinal pathogen, avian pathogenic E. coli (APEC), known to cause systemic infections in chickens, is responsible for large economic losses in the poultry industry worldwide. In order to identify genes involved in the early essential stages of pathogenesis, namely adhesion and colonizati...
Main Authors: | Esther-Maria Antão, Christa Ewers, Doreen Gürlebeck, Rudolf Preisinger, Timo Homeier, Ganwu Li, Lothar H Wieler |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2771359?pdf=render |
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