Social exclusion reliably engages the default network: A meta-analysis of Cyberball
Social exclusion refers to the experience of being disregarded or rejected by others and has wide-ranging negative consequences for well-being and cognition. Cyberball, a game where a ball is virtually tossed between players, then leads to the exclusion of the research participant, is a common metho...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-02-01
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| Series: | NeuroImage |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1053811920311514 |
| _version_ | 1818344185064849408 |
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| author | Laetitia Mwilambwe-Tshilobo R. Nathan Spreng |
| author_facet | Laetitia Mwilambwe-Tshilobo R. Nathan Spreng |
| author_sort | Laetitia Mwilambwe-Tshilobo |
| collection | DOAJ |
| description | Social exclusion refers to the experience of being disregarded or rejected by others and has wide-ranging negative consequences for well-being and cognition. Cyberball, a game where a ball is virtually tossed between players, then leads to the exclusion of the research participant, is a common method used to examine the experience of social exclusion. The neural correlates of social exclusion remain a topic of debate, particularly with regards to the role of the dorsal anterior cingulate cortex (dACC) and the concept of social pain. Here we conducted a quantitative meta-analysis using activation likelihood estimation (ALE) to identify brain activity reliably engaged by social exclusion during Cyberball task performance (Studies = 53; total N = 1,817 participants). Results revealed consistent recruitment in ventral anterior cingulate and posterior cingulate cortex, inferior and superior frontal gyri, posterior insula, and occipital pole. No reliable activity was observed in dACC. Using a probabilistic atlas to define dACC, fewer than 15% of studies reported peak coordinates in dACC. Meta-analytic connectivity mapping suggests patterns of co-activation are consistent with the topography of the default network. Reverse inference for cognition associated with reliable Cyberball activity computed in Neurosynth revealed social exclusion to be associated with cognitive terms Social, Autobiographical, Mental States, and Theory of Mind. Taken together, these findings highlight the role of the default network in social exclusion and warns against interpretations of the dACC as a key region involved in the experience of social exclusion in humans. |
| first_indexed | 2024-12-13T16:42:27Z |
| format | Article |
| id | doaj.art-b4b534a9f1d74d96aad74b028da10da3 |
| institution | Directory Open Access Journal |
| issn | 1095-9572 |
| language | English |
| last_indexed | 2024-12-13T16:42:27Z |
| publishDate | 2021-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | NeuroImage |
| spelling | doaj.art-b4b534a9f1d74d96aad74b028da10da32022-12-21T23:38:15ZengElsevierNeuroImage1095-95722021-02-01227117666Social exclusion reliably engages the default network: A meta-analysis of CyberballLaetitia Mwilambwe-Tshilobo0R. Nathan Spreng1Laboratory of Brain and Cognition, Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada; Corresponding authors.Laboratory of Brain and Cognition, Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada; Departments of Psychiatry and Psychology, McGill University, Montreal, QC, Canada; Douglas Mental Health University Institute, Verdun, QC, Canada; McConnell Brain Imaging Centre, McGill University, Montreal, QC, Canada; Corresponding authors.Social exclusion refers to the experience of being disregarded or rejected by others and has wide-ranging negative consequences for well-being and cognition. Cyberball, a game where a ball is virtually tossed between players, then leads to the exclusion of the research participant, is a common method used to examine the experience of social exclusion. The neural correlates of social exclusion remain a topic of debate, particularly with regards to the role of the dorsal anterior cingulate cortex (dACC) and the concept of social pain. Here we conducted a quantitative meta-analysis using activation likelihood estimation (ALE) to identify brain activity reliably engaged by social exclusion during Cyberball task performance (Studies = 53; total N = 1,817 participants). Results revealed consistent recruitment in ventral anterior cingulate and posterior cingulate cortex, inferior and superior frontal gyri, posterior insula, and occipital pole. No reliable activity was observed in dACC. Using a probabilistic atlas to define dACC, fewer than 15% of studies reported peak coordinates in dACC. Meta-analytic connectivity mapping suggests patterns of co-activation are consistent with the topography of the default network. Reverse inference for cognition associated with reliable Cyberball activity computed in Neurosynth revealed social exclusion to be associated with cognitive terms Social, Autobiographical, Mental States, and Theory of Mind. Taken together, these findings highlight the role of the default network in social exclusion and warns against interpretations of the dACC as a key region involved in the experience of social exclusion in humans.http://www.sciencedirect.com/science/article/pii/S1053811920311514Meta-analysisCyberballSocial exclusionDefault networkMeta-analytic connectivity modelingFunctional MRI |
| spellingShingle | Laetitia Mwilambwe-Tshilobo R. Nathan Spreng Social exclusion reliably engages the default network: A meta-analysis of Cyberball NeuroImage Meta-analysis Cyberball Social exclusion Default network Meta-analytic connectivity modeling Functional MRI |
| title | Social exclusion reliably engages the default network: A meta-analysis of Cyberball |
| title_full | Social exclusion reliably engages the default network: A meta-analysis of Cyberball |
| title_fullStr | Social exclusion reliably engages the default network: A meta-analysis of Cyberball |
| title_full_unstemmed | Social exclusion reliably engages the default network: A meta-analysis of Cyberball |
| title_short | Social exclusion reliably engages the default network: A meta-analysis of Cyberball |
| title_sort | social exclusion reliably engages the default network a meta analysis of cyberball |
| topic | Meta-analysis Cyberball Social exclusion Default network Meta-analytic connectivity modeling Functional MRI |
| url | http://www.sciencedirect.com/science/article/pii/S1053811920311514 |
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