Relationship of rheumatoid arthritis and coronary artery disease in the Korean population: a nationwide cross-sectional study
Abstract Background Rheumatoid arthritis (RA) is known to be associated with coronary artery diseases (CAD). Previous studies of the association between RA and CAD were reported mainly in non-Asian groups. We aimed to examine the prevalence of RA and the relationship between RA and CAD in South Kore...
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| Format: | Article |
| Language: | English |
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BMC
2019-08-01
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| Series: | Advances in Rheumatology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s42358-019-0084-6 |
| _version_ | 1828868655794880512 |
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| author | Tae Hyub Lee Gwan Gyu Song Sung Jae Choi Hongdeok Seok Jae Hyun Jung |
| author_facet | Tae Hyub Lee Gwan Gyu Song Sung Jae Choi Hongdeok Seok Jae Hyun Jung |
| author_sort | Tae Hyub Lee |
| collection | DOAJ |
| description | Abstract Background Rheumatoid arthritis (RA) is known to be associated with coronary artery diseases (CAD). Previous studies of the association between RA and CAD were reported mainly in non-Asian groups. We aimed to examine the prevalence of RA and the relationship between RA and CAD in South Korea. Methods We conducted a nationwide cross-sectional study by using the Korea National Health and Nutrition Examination Survey, which collected data for four years between 2008 and 2012. A total of 25,828 eligible participants were included. To balance the distribution of baseline characteristics, we used propensity score-matching. A multivariable logistic regression model was employed and we calculated the odds ratios (ORs) and 95% confidence intervals (CI) for the odds of the participants with RA on CAD prevalence. Results The prevalence of RA in Korea from 2008 to 2012 was 0.6% and RA was predominant among elderly women. The prevalence of CAD in patients with RA was significantly higher than in general population. After propensity score-matching to balance the confounding factors, RA was significantly associated with CAD (OR 2.97, 95% CI 1.15–7.68, P = 0.02). Conclusions The prevalence of RA in South Korea was comparable to the worldwide data, and the presence of CAD in RA patients was more than two-fold. |
| first_indexed | 2024-12-13T05:34:49Z |
| format | Article |
| id | doaj.art-b4b6ce13f74544568066a09f4b260511 |
| institution | Directory Open Access Journal |
| issn | 2523-3106 |
| language | English |
| last_indexed | 2024-12-13T05:34:49Z |
| publishDate | 2019-08-01 |
| publisher | BMC |
| record_format | Article |
| series | Advances in Rheumatology |
| spelling | doaj.art-b4b6ce13f74544568066a09f4b2605112022-12-21T23:57:57ZengBMCAdvances in Rheumatology2523-31062019-08-015911610.1186/s42358-019-0084-6Relationship of rheumatoid arthritis and coronary artery disease in the Korean population: a nationwide cross-sectional studyTae Hyub Lee0Gwan Gyu Song1Sung Jae Choi2Hongdeok Seok3Jae Hyun Jung4College of Medicine, Chung-Ang UniversityKorea University College of MedicineKorea University College of MedicineDepartment of Occupational and Environmental Medicine, Busan Adventist Hospital, Sahmyook Medical CenterCollege of Medicine, Chung-Ang UniversityAbstract Background Rheumatoid arthritis (RA) is known to be associated with coronary artery diseases (CAD). Previous studies of the association between RA and CAD were reported mainly in non-Asian groups. We aimed to examine the prevalence of RA and the relationship between RA and CAD in South Korea. Methods We conducted a nationwide cross-sectional study by using the Korea National Health and Nutrition Examination Survey, which collected data for four years between 2008 and 2012. A total of 25,828 eligible participants were included. To balance the distribution of baseline characteristics, we used propensity score-matching. A multivariable logistic regression model was employed and we calculated the odds ratios (ORs) and 95% confidence intervals (CI) for the odds of the participants with RA on CAD prevalence. Results The prevalence of RA in Korea from 2008 to 2012 was 0.6% and RA was predominant among elderly women. The prevalence of CAD in patients with RA was significantly higher than in general population. After propensity score-matching to balance the confounding factors, RA was significantly associated with CAD (OR 2.97, 95% CI 1.15–7.68, P = 0.02). Conclusions The prevalence of RA in South Korea was comparable to the worldwide data, and the presence of CAD in RA patients was more than two-fold.http://link.springer.com/article/10.1186/s42358-019-0084-6Rheumatoid arthritisPrevalenceAngina pectorisMyocardial infarction |
| spellingShingle | Tae Hyub Lee Gwan Gyu Song Sung Jae Choi Hongdeok Seok Jae Hyun Jung Relationship of rheumatoid arthritis and coronary artery disease in the Korean population: a nationwide cross-sectional study Advances in Rheumatology Rheumatoid arthritis Prevalence Angina pectoris Myocardial infarction |
| title | Relationship of rheumatoid arthritis and coronary artery disease in the Korean population: a nationwide cross-sectional study |
| title_full | Relationship of rheumatoid arthritis and coronary artery disease in the Korean population: a nationwide cross-sectional study |
| title_fullStr | Relationship of rheumatoid arthritis and coronary artery disease in the Korean population: a nationwide cross-sectional study |
| title_full_unstemmed | Relationship of rheumatoid arthritis and coronary artery disease in the Korean population: a nationwide cross-sectional study |
| title_short | Relationship of rheumatoid arthritis and coronary artery disease in the Korean population: a nationwide cross-sectional study |
| title_sort | relationship of rheumatoid arthritis and coronary artery disease in the korean population a nationwide cross sectional study |
| topic | Rheumatoid arthritis Prevalence Angina pectoris Myocardial infarction |
| url | http://link.springer.com/article/10.1186/s42358-019-0084-6 |
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