Bioprocessing by Decellularized Scaffold Biomaterials in Cultured Meat: A Review
As novel carrier biomaterials, decellularized scaffolds have promising potential in the development of cellular agriculture and edible cell-cultured meat applications. Decellularized scaffold biomaterials have characteristics of high biocompatibility, bio-degradation, biological safety and various b...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-12-01
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| Series: | Bioengineering |
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| Online Access: | https://www.mdpi.com/2306-5354/9/12/787 |
| _version_ | 1797461440781615104 |
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| author | Hongyun Lu Keqin Ying Ying Shi Donghong Liu Qihe Chen |
| author_facet | Hongyun Lu Keqin Ying Ying Shi Donghong Liu Qihe Chen |
| author_sort | Hongyun Lu |
| collection | DOAJ |
| description | As novel carrier biomaterials, decellularized scaffolds have promising potential in the development of cellular agriculture and edible cell-cultured meat applications. Decellularized scaffold biomaterials have characteristics of high biocompatibility, bio-degradation, biological safety and various bioactivities, which could potentially compensate for the shortcomings of synthetic bio-scaffold materials. They can provide suitable microstructure and mechanical support for cell adhesion, differentiation and proliferation. To our best knowledge, the preparation and application of plant and animal decellularized scaffolds have not been summarized. Herein, a comprehensive presentation of the principles, preparation methods and application progress of animal-derived and plant-derived decellularized scaffolds has been reported in detail. Additionally, their application in the culture of skeletal muscle, fat and connective tissue, which constitute the main components of edible cultured meat, have also been generally discussed. We also illustrate the potential applications and prospects of decellularized scaffold materials in future foods. This review of cultured meat and decellularized scaffold biomaterials provides new insight and great potential research prospects in food application and cellular agriculture. |
| first_indexed | 2024-03-09T17:19:27Z |
| format | Article |
| id | doaj.art-b4b736bc12c0429a850dc0a9df45f132 |
| institution | Directory Open Access Journal |
| issn | 2306-5354 |
| language | English |
| last_indexed | 2024-03-09T17:19:27Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Bioengineering |
| spelling | doaj.art-b4b736bc12c0429a850dc0a9df45f1322023-11-24T13:21:02ZengMDPI AGBioengineering2306-53542022-12-0191278710.3390/bioengineering9120787Bioprocessing by Decellularized Scaffold Biomaterials in Cultured Meat: A ReviewHongyun Lu0Keqin Ying1Ying Shi2Donghong Liu3Qihe Chen4Department of Food Science and Nutrition, Zhejiang University, Hangzhou 310058, ChinaCollege of Food Science and Technology, Nanjing University, Nanjing 210095, ChinaDepartment of Food Science and Nutrition, Zhejiang University, Hangzhou 310058, ChinaDepartment of Food Science and Nutrition, Zhejiang University, Hangzhou 310058, ChinaDepartment of Food Science and Nutrition, Zhejiang University, Hangzhou 310058, ChinaAs novel carrier biomaterials, decellularized scaffolds have promising potential in the development of cellular agriculture and edible cell-cultured meat applications. Decellularized scaffold biomaterials have characteristics of high biocompatibility, bio-degradation, biological safety and various bioactivities, which could potentially compensate for the shortcomings of synthetic bio-scaffold materials. They can provide suitable microstructure and mechanical support for cell adhesion, differentiation and proliferation. To our best knowledge, the preparation and application of plant and animal decellularized scaffolds have not been summarized. Herein, a comprehensive presentation of the principles, preparation methods and application progress of animal-derived and plant-derived decellularized scaffolds has been reported in detail. Additionally, their application in the culture of skeletal muscle, fat and connective tissue, which constitute the main components of edible cultured meat, have also been generally discussed. We also illustrate the potential applications and prospects of decellularized scaffold materials in future foods. This review of cultured meat and decellularized scaffold biomaterials provides new insight and great potential research prospects in food application and cellular agriculture.https://www.mdpi.com/2306-5354/9/12/787cell-cultured meatbiomaterialcellular agriculturedecellularized scaffoldsfuture fooddecellularization |
| spellingShingle | Hongyun Lu Keqin Ying Ying Shi Donghong Liu Qihe Chen Bioprocessing by Decellularized Scaffold Biomaterials in Cultured Meat: A Review Bioengineering cell-cultured meat biomaterial cellular agriculture decellularized scaffolds future food decellularization |
| title | Bioprocessing by Decellularized Scaffold Biomaterials in Cultured Meat: A Review |
| title_full | Bioprocessing by Decellularized Scaffold Biomaterials in Cultured Meat: A Review |
| title_fullStr | Bioprocessing by Decellularized Scaffold Biomaterials in Cultured Meat: A Review |
| title_full_unstemmed | Bioprocessing by Decellularized Scaffold Biomaterials in Cultured Meat: A Review |
| title_short | Bioprocessing by Decellularized Scaffold Biomaterials in Cultured Meat: A Review |
| title_sort | bioprocessing by decellularized scaffold biomaterials in cultured meat a review |
| topic | cell-cultured meat biomaterial cellular agriculture decellularized scaffolds future food decellularization |
| url | https://www.mdpi.com/2306-5354/9/12/787 |
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