Inhalation anesthesia and hepatoprotection in patients undergoing right hepatectomy for living donor liver transplantation

Objective: To verify if inhalation anesthesia administered duringright lobe hepatectomy for living donor transplantation, asperformed at Hospital Israelita Albert Einstein, could attenuatepostoperative liver dysfunction in these patients. Methods: Weretrospectively reviewed perioperative data of 56...

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Main Authors: Flávio Takaoka, Paulo Celso Bosco Massarollo, Sérgio Mies, Alexandre Teruya
Format: Article
Language:English
Published: Instituto Israelita de Ensino e Pesquisa Albert Einstein 2005-06-01
Series:Einstein (São Paulo)
Subjects:
Online Access:http://www.einstein.br/revista/biblioteca/artigos/vol3/num_2/Vol3_N2_P87.pdf
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author Flávio Takaoka
Paulo Celso Bosco Massarollo
Sérgio Mies
Alexandre Teruya
author_facet Flávio Takaoka
Paulo Celso Bosco Massarollo
Sérgio Mies
Alexandre Teruya
author_sort Flávio Takaoka
collection DOAJ
description Objective: To verify if inhalation anesthesia administered duringright lobe hepatectomy for living donor transplantation, asperformed at Hospital Israelita Albert Einstein, could attenuatepostoperative liver dysfunction in these patients. Methods: Weretrospectively reviewed perioperative data of 56 patients whounderwent right lobe hepatectomy for living donortransplantation. Patients were separated into two groups: onegroup received inhalation anesthesia, and another received totalintravenous anesthesia. Results: Standard liver function tests:prothrombin time, platelet count, ALT/AST were not statisticallydifferent in patients who received inhalation anesthesia comparedto total intravenous anesthesia in the early postoperative period.Conclusion: Hepatoprotective properties of inhalation anesthesiacould not be demonstrated in this retrospective study whencompared to intravenous anesthesia in patients submitted to rightlobe hepatectomy. Increased safety of this procedure for the donoris mandatory. Therefore, strategies resulting in preservation ofliver function, like preconditioning, deserve further studies.
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spelling doaj.art-b4b86b9c7bce445ba70b22c2b044eb712022-12-22T03:32:54ZengInstituto Israelita de Ensino e Pesquisa Albert EinsteinEinstein (São Paulo)1679-45082005-06-01328790Inhalation anesthesia and hepatoprotection in patients undergoing right hepatectomy for living donor liver transplantationFlávio TakaokaPaulo Celso Bosco MassarolloSérgio MiesAlexandre TeruyaObjective: To verify if inhalation anesthesia administered duringright lobe hepatectomy for living donor transplantation, asperformed at Hospital Israelita Albert Einstein, could attenuatepostoperative liver dysfunction in these patients. Methods: Weretrospectively reviewed perioperative data of 56 patients whounderwent right lobe hepatectomy for living donortransplantation. Patients were separated into two groups: onegroup received inhalation anesthesia, and another received totalintravenous anesthesia. Results: Standard liver function tests:prothrombin time, platelet count, ALT/AST were not statisticallydifferent in patients who received inhalation anesthesia comparedto total intravenous anesthesia in the early postoperative period.Conclusion: Hepatoprotective properties of inhalation anesthesiacould not be demonstrated in this retrospective study whencompared to intravenous anesthesia in patients submitted to rightlobe hepatectomy. Increased safety of this procedure for the donoris mandatory. Therefore, strategies resulting in preservation ofliver function, like preconditioning, deserve further studies.http://www.einstein.br/revista/biblioteca/artigos/vol3/num_2/Vol3_N2_P87.pdfInhalation anesthesiaIntravenous anesthesiaLiver transplantation
spellingShingle Flávio Takaoka
Paulo Celso Bosco Massarollo
Sérgio Mies
Alexandre Teruya
Inhalation anesthesia and hepatoprotection in patients undergoing right hepatectomy for living donor liver transplantation
Einstein (São Paulo)
Inhalation anesthesia
Intravenous anesthesia
Liver transplantation
title Inhalation anesthesia and hepatoprotection in patients undergoing right hepatectomy for living donor liver transplantation
title_full Inhalation anesthesia and hepatoprotection in patients undergoing right hepatectomy for living donor liver transplantation
title_fullStr Inhalation anesthesia and hepatoprotection in patients undergoing right hepatectomy for living donor liver transplantation
title_full_unstemmed Inhalation anesthesia and hepatoprotection in patients undergoing right hepatectomy for living donor liver transplantation
title_short Inhalation anesthesia and hepatoprotection in patients undergoing right hepatectomy for living donor liver transplantation
title_sort inhalation anesthesia and hepatoprotection in patients undergoing right hepatectomy for living donor liver transplantation
topic Inhalation anesthesia
Intravenous anesthesia
Liver transplantation
url http://www.einstein.br/revista/biblioteca/artigos/vol3/num_2/Vol3_N2_P87.pdf
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AT sergiomies inhalationanesthesiaandhepatoprotectioninpatientsundergoingrighthepatectomyforlivingdonorlivertransplantation
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