Chemical combinations elucidate pathway interactions and regulation relevant to Hepatitis C replication
The search for effective Hepatitis C antiviral therapies has recently focused on host sterol metabolism and protein prenylation pathways that indirectly affect viral replication. However, inhibition of the sterol pathway with statin drugs has not yielded consistent results in patients. Here, we pres...
Main Authors: | Christopher M Owens, Christina Mawhinney, Jill M Grenier, Ralf Altmeyer, Margaret S Lee, Alexis A Borisy, Joseph Lehár, Lisa M Johansen |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2010-01-01
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Series: | Molecular Systems Biology |
Subjects: | |
Online Access: | https://doi.org/10.1038/msb.2010.32 |
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