CD13 Inhibition Enhances Cytotoxic Effect of Chemotherapy Agents

CD13 Inhibition Enhances Cytotoxic Effect of Chemotherapy Agents

Multidrug resistance (MDR) of hepatocellular carcinoma is a serious problem. Although CD13 is a biomarker in human liver cancer stem cells, the relationship between CD13 and MDR remains uncertain. This study uses liver cancer cell model to understand the role of CD13 in enhancing the cytotoxic effec...

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Bibliographic Details
Main Authors: Jian Zhang, Chunyan Fang, Meihua Qu, Huina Wu, Xuejuan Wang, Hongan Zhang, Hui Ma, Zhaolin Zhang, Yongxue Huang, Lihong Shi, Shujuan Liang, Zhiqin Gao, Weiguo Song, Xuejian Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Pharmacology
Subjects:
CD13
MDR
bestatin
BC-02
5FU
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01042/full

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