Diagnostic Methods for Detection of Cotinine Level in Tobacco Users: A Review
The greatest disease-producing product known to man is tobacco. It is a cause of many oral diseases and adverse oral conditions. In India, tobacco is available in smokeless and smoking form. Tobacco contains nicotine which metabolises to form a toxic alkaloid i.e. cotinine. It stimulates autonomic...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2016-03-01
|
| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/7423/17360_CE(Ra1)_F(AK)_PF1(EKAK)_PFA(AK)_PF2(PAG).pdf |
| _version_ | 1811340314332364800 |
|---|---|
| author | Mitali Raja Aarti Garg Pramod Yadav Kunal Jha Sahil Handa |
| author_facet | Mitali Raja Aarti Garg Pramod Yadav Kunal Jha Sahil Handa |
| author_sort | Mitali Raja |
| collection | DOAJ |
| description | The greatest disease-producing product known to man is tobacco. It is a cause of many oral diseases and adverse oral conditions. In
India, tobacco is available in smokeless and smoking form. Tobacco contains nicotine which metabolises to form a toxic alkaloid i.e.
cotinine. It stimulates autonomic ganglia and central nervous system. Cotinine is the best indicator of tobacco smoke exposure. Various
methods are used to measure cotinine level in blood, saliva and urine such as high performance liquid chromatography, colorimetric
assay, gas chromatography, NicAlert saliva test, etc.
Thus such wide range of methods for cotinine detection in tobacco users requires a detailed discussion regarding their utility. This review
will help readers to compare various methods for cotinine detection and enable them to make scientifically informative decision. |
| first_indexed | 2024-04-13T18:40:06Z |
| format | Article |
| id | doaj.art-b4beabeb3f9c4ee69ac70805cab114fb |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-04-13T18:40:06Z |
| publishDate | 2016-03-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-b4beabeb3f9c4ee69ac70805cab114fb2022-12-22T02:34:45ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2016-03-01103ZE04ZE0610.7860/JCDR/2016/17360.7423Diagnostic Methods for Detection of Cotinine Level in Tobacco Users: A ReviewMitali Raja0Aarti Garg1Pramod Yadav2Kunal Jha3Sahil Handa4Senior Lecturer, Department of Public Health Dentistry, Rama Dental College Hospital and Research Centre, Kanpur, Uttar Pradesh, India.Senior Lecturer, Department of Pedodontics and Preventive Dentistry, Jaipur Dental College, Jaipur, India.Assistant Professor, Department of Periodontology and Public Health Dentistry, Dr ZA Dental College, AMU, Aligarh, India.Senior Lecturer, Department of Public Health Dentistry, Kalinga Institute of Dental Sciences, KIIT University, Bhubaneshwar, India.Senior Lecturer, Department of Public Health Dentistry, College of Dental Science and Hospital, Rau, Indore, Madhya Pradesh, India.The greatest disease-producing product known to man is tobacco. It is a cause of many oral diseases and adverse oral conditions. In India, tobacco is available in smokeless and smoking form. Tobacco contains nicotine which metabolises to form a toxic alkaloid i.e. cotinine. It stimulates autonomic ganglia and central nervous system. Cotinine is the best indicator of tobacco smoke exposure. Various methods are used to measure cotinine level in blood, saliva and urine such as high performance liquid chromatography, colorimetric assay, gas chromatography, NicAlert saliva test, etc. Thus such wide range of methods for cotinine detection in tobacco users requires a detailed discussion regarding their utility. This review will help readers to compare various methods for cotinine detection and enable them to make scientifically informative decision.https://jcdr.net/articles/PDF/7423/17360_CE(Ra1)_F(AK)_PF1(EKAK)_PFA(AK)_PF2(PAG).pdfnicotinetobacco productstoxic alkaloid |
| spellingShingle | Mitali Raja Aarti Garg Pramod Yadav Kunal Jha Sahil Handa Diagnostic Methods for Detection of Cotinine Level in Tobacco Users: A Review Journal of Clinical and Diagnostic Research nicotine tobacco products toxic alkaloid |
| title | Diagnostic Methods for Detection of Cotinine Level in Tobacco Users: A Review |
| title_full | Diagnostic Methods for Detection of Cotinine Level in Tobacco Users: A Review |
| title_fullStr | Diagnostic Methods for Detection of Cotinine Level in Tobacco Users: A Review |
| title_full_unstemmed | Diagnostic Methods for Detection of Cotinine Level in Tobacco Users: A Review |
| title_short | Diagnostic Methods for Detection of Cotinine Level in Tobacco Users: A Review |
| title_sort | diagnostic methods for detection of cotinine level in tobacco users a review |
| topic | nicotine tobacco products toxic alkaloid |
| url | https://jcdr.net/articles/PDF/7423/17360_CE(Ra1)_F(AK)_PF1(EKAK)_PFA(AK)_PF2(PAG).pdf |
| work_keys_str_mv | AT mitaliraja diagnosticmethodsfordetectionofcotininelevelintobaccousersareview AT aartigarg diagnosticmethodsfordetectionofcotininelevelintobaccousersareview AT pramodyadav diagnosticmethodsfordetectionofcotininelevelintobaccousersareview AT kunaljha diagnosticmethodsfordetectionofcotininelevelintobaccousersareview AT sahilhanda diagnosticmethodsfordetectionofcotininelevelintobaccousersareview |