MicroRNA-mediated attenuation of branched-chain amino acid catabolism promotes ferroptosis in chronic kidney disease

MicroRNA-mediated attenuation of branched-chain amino acid catabolism promotes ferroptosis in chronic kidney disease

Abstract Chronic kidney disease can develop from kidney injury incident to chemotherapy with cisplatin, which complicates the prognosis of cancer patients. MicroRNAs regulate gene expression by pairing with specific sets of messenger RNAs. Therefore, elucidating direct physical interactions between...

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Bibliographic Details
Main Authors:	Hisakatsu Sone, Tae Jin Lee, Byung Rho Lee, Dan Heo, Sekyung Oh, Sang-Ho Kwon
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-11-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-023-43529-z

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