The role of the small intestine in the development of metabolic syndrome

AIM: To comprehensively investigate the function of the small intestine (SI) in metabolic syndrome (MS). /MATERIAL AND METHODS: Seventy-eight patients with MS were examined using, in addition to clinical studies, comprehensive ones of the function of SI: evaluation of its motor, digestive, and absor...

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Main Authors: Ia M Vakhrushev, M V Liapina
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2012-12-01
Series:Терапевтический архив
Subjects:
Online Access:https://ter-arkhiv.ru/0040-3660/article/view/31161
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author Ia M Vakhrushev
M V Liapina
author_facet Ia M Vakhrushev
M V Liapina
author_sort Ia M Vakhrushev
collection DOAJ
description AIM: To comprehensively investigate the function of the small intestine (SI) in metabolic syndrome (MS). /MATERIAL AND METHODS: Seventy-eight patients with MS were examined using, in addition to clinical studies, comprehensive ones of the function of SI: evaluation of its motor, digestive, and absorptive functions. The specific features of the hormonal and autonomic status were studied in the patients with MS /RESULTS: Clinical local and common signs of SI lesion were seen in 82.9% of the patients. Examination of SI function revealed its impairments at all stages of hydrolysis and resorption in the presence of hypomotor dyskinesia in the postprandial period and hypersympaticotonia in the patients with MS. New pathogenic patterns were found in relation to the role of hormones in intestinal digestive and absorptive dysfunctions in MS /CONCLUSION: The findings may suggest that SI functional changes found in MS are an important component of its complex pathogenetic circle.
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spelling doaj.art-b4c144950feb42848875d3fed5e4a5522022-12-22T03:05:54Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422012-12-018412626528177The role of the small intestine in the development of metabolic syndromeIa M VakhrushevM V LiapinaAIM: To comprehensively investigate the function of the small intestine (SI) in metabolic syndrome (MS). /MATERIAL AND METHODS: Seventy-eight patients with MS were examined using, in addition to clinical studies, comprehensive ones of the function of SI: evaluation of its motor, digestive, and absorptive functions. The specific features of the hormonal and autonomic status were studied in the patients with MS /RESULTS: Clinical local and common signs of SI lesion were seen in 82.9% of the patients. Examination of SI function revealed its impairments at all stages of hydrolysis and resorption in the presence of hypomotor dyskinesia in the postprandial period and hypersympaticotonia in the patients with MS. New pathogenic patterns were found in relation to the role of hormones in intestinal digestive and absorptive dysfunctions in MS /CONCLUSION: The findings may suggest that SI functional changes found in MS are an important component of its complex pathogenetic circle.https://ter-arkhiv.ru/0040-3660/article/view/31161metabolic syndromesmall intestinal functionhormonesautonomic status
spellingShingle Ia M Vakhrushev
M V Liapina
The role of the small intestine in the development of metabolic syndrome
Терапевтический архив
metabolic syndrome
small intestinal function
hormones
autonomic status
title The role of the small intestine in the development of metabolic syndrome
title_full The role of the small intestine in the development of metabolic syndrome
title_fullStr The role of the small intestine in the development of metabolic syndrome
title_full_unstemmed The role of the small intestine in the development of metabolic syndrome
title_short The role of the small intestine in the development of metabolic syndrome
title_sort role of the small intestine in the development of metabolic syndrome
topic metabolic syndrome
small intestinal function
hormones
autonomic status
url https://ter-arkhiv.ru/0040-3660/article/view/31161
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