Risk of Early Birth among Women with a Urinary Tract Infection: A Retrospective Cohort Study
Objective The aim of the study is to evaluate the risk of preterm birth (PTB, <37 weeks) and early term (37 and 38 weeks) birth among women with an emergency department (ED) visit or hospitalization with a urinary tract infection (UTI) by trimester of pregnancy. Methods The primary sam...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Thieme Medical Publishers, Inc.
2021-01-01
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| Series: | American Journal of Perinatology Reports |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1721668 |
| _version_ | 1818963998624710656 |
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| author | Rebecca J. Baer Nichole Nidey Gretchen Bandoli Brittany D. Chambers Christina D. Chambers Sky Feuer Deborah Karasek Scott P. Oltman Larry Rand Kelli K. Ryckman Laura L. Jelliffe-Pawlowski |
| author_facet | Rebecca J. Baer Nichole Nidey Gretchen Bandoli Brittany D. Chambers Christina D. Chambers Sky Feuer Deborah Karasek Scott P. Oltman Larry Rand Kelli K. Ryckman Laura L. Jelliffe-Pawlowski |
| author_sort | Rebecca J. Baer |
| collection | DOAJ |
| description | Objective The aim of the study is to evaluate the risk of preterm birth (PTB, <37 weeks) and early term (37 and 38 weeks) birth among women with an emergency department (ED) visit or hospitalization with a urinary tract infection (UTI) by trimester of pregnancy.
Methods The primary sample was selected from births in California between 2011 and 2017. UTIs were identified from the ED or hospital discharge records. Risk of PTB, by subtype, and early term birth were evaluated by trimester of pregnancy and by type of visit using log-linear regression. Risk ratios were adjusted for maternal factors. Antibiotic usage was examined in a population of privately insured women from Iowa.
Results Women with a UTI during pregnancy were at elevated risk of a birth <32 weeks, 32 to 36 weeks, and 37 to 38 weeks (adjusted risk ratios [aRRs] 1.1–1.4). Of the women with a diagnostic code for multiple bacterial species, 28.8% had a PTB. A UTI diagnosis elevated risk of PTB regardless of antibiotic treatment (aRR 1.4 for treated, aRR 1.5 for untreated).
Conclusion UTIs are associated with early birth. This association is present regardless of the trimester of pregnancy, type of PTB, and antibiotic treatment. |
| first_indexed | 2024-12-20T12:54:07Z |
| format | Article |
| id | doaj.art-b4c2abd857b9432cb393b67bd9390261 |
| institution | Directory Open Access Journal |
| issn | 2157-6998 2157-7005 |
| language | English |
| last_indexed | 2024-12-20T12:54:07Z |
| publishDate | 2021-01-01 |
| publisher | Thieme Medical Publishers, Inc. |
| record_format | Article |
| series | American Journal of Perinatology Reports |
| spelling | doaj.art-b4c2abd857b9432cb393b67bd93902612022-12-21T19:40:06ZengThieme Medical Publishers, Inc.American Journal of Perinatology Reports2157-69982157-70052021-01-011101e5e1410.1055/s-0040-1721668Risk of Early Birth among Women with a Urinary Tract Infection: A Retrospective Cohort StudyRebecca J. Baer0Nichole Nidey1Gretchen Bandoli2Brittany D. Chambers3Christina D. Chambers4Sky Feuer5Deborah Karasek6Scott P. Oltman7Larry Rand8Kelli K. Ryckman9Laura L. Jelliffe-Pawlowski10Department of Pediatrics, University of California San Diego, La Jolla, CaliforniaDepartment of Epidemiology, University of Iowa, Iowa City, IowaDepartment of Pediatrics, University of California San Diego, La Jolla, CaliforniaThe California Preterm Birth Initiative, University of California San Francisco, San Francisco, CaliforniaDepartment of Pediatrics, University of California San Diego, La Jolla, CaliforniaDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, CaliforniaDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, CaliforniaThe California Preterm Birth Initiative, University of California San Francisco, San Francisco, CaliforniaDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, CaliforniaDepartment of Epidemiology, University of Iowa, Iowa City, IowaThe California Preterm Birth Initiative, University of California San Francisco, San Francisco, CaliforniaObjective The aim of the study is to evaluate the risk of preterm birth (PTB, <37 weeks) and early term (37 and 38 weeks) birth among women with an emergency department (ED) visit or hospitalization with a urinary tract infection (UTI) by trimester of pregnancy. Methods The primary sample was selected from births in California between 2011 and 2017. UTIs were identified from the ED or hospital discharge records. Risk of PTB, by subtype, and early term birth were evaluated by trimester of pregnancy and by type of visit using log-linear regression. Risk ratios were adjusted for maternal factors. Antibiotic usage was examined in a population of privately insured women from Iowa. Results Women with a UTI during pregnancy were at elevated risk of a birth <32 weeks, 32 to 36 weeks, and 37 to 38 weeks (adjusted risk ratios [aRRs] 1.1–1.4). Of the women with a diagnostic code for multiple bacterial species, 28.8% had a PTB. A UTI diagnosis elevated risk of PTB regardless of antibiotic treatment (aRR 1.4 for treated, aRR 1.5 for untreated). Conclusion UTIs are associated with early birth. This association is present regardless of the trimester of pregnancy, type of PTB, and antibiotic treatment.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1721668preterm birthearly term birthurinary tract infectionbacterial speciestrimester of infection |
| spellingShingle | Rebecca J. Baer Nichole Nidey Gretchen Bandoli Brittany D. Chambers Christina D. Chambers Sky Feuer Deborah Karasek Scott P. Oltman Larry Rand Kelli K. Ryckman Laura L. Jelliffe-Pawlowski Risk of Early Birth among Women with a Urinary Tract Infection: A Retrospective Cohort Study American Journal of Perinatology Reports preterm birth early term birth urinary tract infection bacterial species trimester of infection |
| title | Risk of Early Birth among Women with a Urinary Tract Infection: A Retrospective Cohort Study |
| title_full | Risk of Early Birth among Women with a Urinary Tract Infection: A Retrospective Cohort Study |
| title_fullStr | Risk of Early Birth among Women with a Urinary Tract Infection: A Retrospective Cohort Study |
| title_full_unstemmed | Risk of Early Birth among Women with a Urinary Tract Infection: A Retrospective Cohort Study |
| title_short | Risk of Early Birth among Women with a Urinary Tract Infection: A Retrospective Cohort Study |
| title_sort | risk of early birth among women with a urinary tract infection a retrospective cohort study |
| topic | preterm birth early term birth urinary tract infection bacterial species trimester of infection |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1721668 |
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