Primary Sjögren′s syndrome manifesting as multiple cranial neuropathies: MRI findings
We report a case of primary Sjögren′s syndrome presenting with multiple cranial nerve palsies and radiological evidence of cranial pachymeningitis and hypophysitis. A 47-year-old woman developed right sensory neural hearing loss followed, 2 months later, by right facial palsy. Cr...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2009-01-01
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| Series: | Annals of Indian Academy of Neurology |
| Subjects: | |
| Online Access: | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2009;volume=12;issue=2;spage=124;epage=126;aulast=Ashraf |
| _version_ | 1818683446866739200 |
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| author | Ashraf V Bhasi Ramesh Kumar R Girija A |
| author_facet | Ashraf V Bhasi Ramesh Kumar R Girija A |
| author_sort | Ashraf V |
| collection | DOAJ |
| description | We report a case of primary Sjögren′s syndrome presenting with multiple cranial nerve palsies and radiological evidence of cranial pachymeningitis and hypophysitis. A 47-year-old woman developed right sensory neural hearing loss followed, 2 months later, by right facial palsy. Cranial magnetic resonance imaging showed features of pachymeningitis and pituitary gland infiltration. The diagnosis of primary Sjögren′s syndrome was confirmed by demonstrating positive SS-A and SS-B antibodies and histological evidence of lymphocytic infiltration of the sublabial salivary gland. During the 2-year follow-up, the patient had transient VI<sup> th</sup> , IX<sup> th</sup> , X<sup> th</sup> , and XII<sup> th</sup> cranial nerve palsies. Sjögren′s syndrome should be considered in the differential diagnosis of patients presenting with multiple recurrent cranial nerve palsies, even if prominent sicca symptoms are absent. |
| first_indexed | 2024-12-17T10:34:52Z |
| format | Article |
| id | doaj.art-b4c7399ad8fc46478f0ac6df31a80a61 |
| institution | Directory Open Access Journal |
| issn | 0972-2327 1998-3549 |
| language | English |
| last_indexed | 2024-12-17T10:34:52Z |
| publishDate | 2009-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Indian Academy of Neurology |
| spelling | doaj.art-b4c7399ad8fc46478f0ac6df31a80a612022-12-21T21:52:25ZengWolters Kluwer Medknow PublicationsAnnals of Indian Academy of Neurology0972-23271998-35492009-01-01122124126Primary Sjögren′s syndrome manifesting as multiple cranial neuropathies: MRI findingsAshraf VBhasi RameshKumar RGirija AWe report a case of primary Sjögren′s syndrome presenting with multiple cranial nerve palsies and radiological evidence of cranial pachymeningitis and hypophysitis. A 47-year-old woman developed right sensory neural hearing loss followed, 2 months later, by right facial palsy. Cranial magnetic resonance imaging showed features of pachymeningitis and pituitary gland infiltration. The diagnosis of primary Sjögren′s syndrome was confirmed by demonstrating positive SS-A and SS-B antibodies and histological evidence of lymphocytic infiltration of the sublabial salivary gland. During the 2-year follow-up, the patient had transient VI<sup> th</sup> , IX<sup> th</sup> , X<sup> th</sup> , and XII<sup> th</sup> cranial nerve palsies. Sjögren′s syndrome should be considered in the differential diagnosis of patients presenting with multiple recurrent cranial nerve palsies, even if prominent sicca symptoms are absent.http://www.annalsofian.org/article.asp?issn=0972-2327;year=2009;volume=12;issue=2;spage=124;epage=126;aulast=AshrafCranial pachymeningitis<b> </b> multiple cranial nerve palsies<b> </b> primary<b> </b> Sjögren syndrome |
| spellingShingle | Ashraf V Bhasi Ramesh Kumar R Girija A Primary Sjögren′s syndrome manifesting as multiple cranial neuropathies: MRI findings Annals of Indian Academy of Neurology Cranial pachymeningitis <b> </b> multiple cranial nerve palsies <b> </b> primary<b> </b> Sjögren syndrome |
| title | Primary Sjögren′s syndrome manifesting as multiple cranial neuropathies: MRI findings |
| title_full | Primary Sjögren′s syndrome manifesting as multiple cranial neuropathies: MRI findings |
| title_fullStr | Primary Sjögren′s syndrome manifesting as multiple cranial neuropathies: MRI findings |
| title_full_unstemmed | Primary Sjögren′s syndrome manifesting as multiple cranial neuropathies: MRI findings |
| title_short | Primary Sjögren′s syndrome manifesting as multiple cranial neuropathies: MRI findings |
| title_sort | primary sj 246 gren x2032 s syndrome manifesting as multiple cranial neuropathies mri findings |
| topic | Cranial pachymeningitis <b> </b> multiple cranial nerve palsies <b> </b> primary<b> </b> Sjögren syndrome |
| url | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2009;volume=12;issue=2;spage=124;epage=126;aulast=Ashraf |
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