Novel Protein-Based Vaccine against Self-Antigen Reduces the Formation of Sporadic Colon Adenomas in Mice

Novel Protein-Based Vaccine against Self-Antigen Reduces the Formation of Sporadic Colon Adenomas in Mice

Novel immunopreventive strategies are emerging that show great promise for conferring long-term protection to individuals at high risk of developing colorectal cancer. The KISIMA vaccine platform utilizes a chimeric protein comprising: (1) a selected tumor antigen; (2) a cell-penetrating peptide to...

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Bibliographic Details
Main Authors: Elodie Belnoue, Alyssa A. Leystra, Susanna Carboni, Harry S. Cooper, Rodrigo T. Macedo, Kristen N. Harvey, Kimberly B. Colby, Kerry S. Campbell, Lisa A. Vanderveer, Margie L. Clapper, Madiha Derouazi
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
cancer vaccine
colon cancer
mouse model
Ascl2
T cell response
humoral response
Online Access:https://www.mdpi.com/2072-6694/13/4/845

Internet

https://www.mdpi.com/2072-6694/13/4/845

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