Renal Excretion of Water-soluble Contrast Media After Enema in the Neonatal Period
When abdominal distention occurs or bowel obstruction is suspected in the neonatal period, a water-soluble contrast enema is helpful for diagnostic and therapeutic purposes. The water-soluble contrast medium is evacuated through the anus as well as excreted via the kidneys in some babies. This study...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2014-08-01
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| Series: | Pediatrics and Neonatology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1875957213001873 |
| _version_ | 1811303712503627776 |
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| author | Hee Sun Kim Bo-Kyung Je Sang Hoon Cha Byung Min Choi Ki Yeol Lee Seung Hwa Lee |
| author_facet | Hee Sun Kim Bo-Kyung Je Sang Hoon Cha Byung Min Choi Ki Yeol Lee Seung Hwa Lee |
| author_sort | Hee Sun Kim |
| collection | DOAJ |
| description | When abdominal distention occurs or bowel obstruction is suspected in the neonatal period, a water-soluble contrast enema is helpful for diagnostic and therapeutic purposes. The water-soluble contrast medium is evacuated through the anus as well as excreted via the kidneys in some babies. This study was designed to evaluate the incidence of renal excretion after enemas using water-soluble contrast media and presume the causes.
Methods: Contrast enemas using diluted water-soluble contrast media were performed in 23 patients under 2 months of age. After the enema, patients were followed with simple abdominal radiographs to assess the improvement in bowel distention, and we could also detect the presence of renal excretion of contrast media on the radiographs. Reviewing the medical records and imaging studies, including enemas and consecutive abdominal radiographs, we evaluated the incidence of renal excretion of water-soluble contrast media and counted the stay duration of contrast media in urinary tract, bladder, and colon.
Results: Among 23 patients, 12 patients (52%) experienced the renal excretion of water-soluble contrast media. In these patients, stay-in-bladder durations of contrast media were 1-3 days and stay-in-colon durations of contrast media were 1-10 days, while stay-in-colon durations of contrast media were 1-3 days in the patients not showing renal excretion of contrast media. The Mann-Whitney test for stay-in-colon durations demonstrated the later evacuation of contrast media in the patients with renal excretion of contrast media (p = 0.07). The review of the medical records showed that 19 patients were finally diagnosed as intestinal diseases, including Hirschsprung's disease, meconium ileum, meconium plug syndrome, and small bowel atresia or stenosis. Fisher's exact test between the presence of urinary excretion and intestinal diseases indicated a statistically significant difference (p = 0.04).
Conclusion: The intestinal diseases causing bowel obstruction may increase the water-soluble contrast media's dwell time in the bowel and also increase urinary excretion. |
| first_indexed | 2024-04-13T07:51:50Z |
| format | Article |
| id | doaj.art-b4c95e347ff242e8b51732758cbb5243 |
| institution | Directory Open Access Journal |
| issn | 1875-9572 |
| language | English |
| last_indexed | 2024-04-13T07:51:50Z |
| publishDate | 2014-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Pediatrics and Neonatology |
| spelling | doaj.art-b4c95e347ff242e8b51732758cbb52432022-12-22T02:55:30ZengElsevierPediatrics and Neonatology1875-95722014-08-0155425626110.1016/j.pedneo.2013.07.012Renal Excretion of Water-soluble Contrast Media After Enema in the Neonatal PeriodHee Sun Kim0Bo-Kyung Je1Sang Hoon Cha2Byung Min Choi3Ki Yeol Lee4Seung Hwa Lee5Department of Radiology, Korea University Hospital, Ansan, Gyeonggido, Republic of KoreaDepartment of Radiology, Korea University Hospital, Ansan, Gyeonggido, Republic of KoreaDepartment of Radiology, Korea University Hospital, Ansan, Gyeonggido, Republic of KoreaDepartment of Pediatrics, Korea University Hospital, Ansan, Gyeonggido, Republic of KoreaDepartment of Radiology, Korea University Hospital, Ansan, Gyeonggido, Republic of KoreaDepartment of Radiology, Korea University Hospital, Ansan, Gyeonggido, Republic of KoreaWhen abdominal distention occurs or bowel obstruction is suspected in the neonatal period, a water-soluble contrast enema is helpful for diagnostic and therapeutic purposes. The water-soluble contrast medium is evacuated through the anus as well as excreted via the kidneys in some babies. This study was designed to evaluate the incidence of renal excretion after enemas using water-soluble contrast media and presume the causes. Methods: Contrast enemas using diluted water-soluble contrast media were performed in 23 patients under 2 months of age. After the enema, patients were followed with simple abdominal radiographs to assess the improvement in bowel distention, and we could also detect the presence of renal excretion of contrast media on the radiographs. Reviewing the medical records and imaging studies, including enemas and consecutive abdominal radiographs, we evaluated the incidence of renal excretion of water-soluble contrast media and counted the stay duration of contrast media in urinary tract, bladder, and colon. Results: Among 23 patients, 12 patients (52%) experienced the renal excretion of water-soluble contrast media. In these patients, stay-in-bladder durations of contrast media were 1-3 days and stay-in-colon durations of contrast media were 1-10 days, while stay-in-colon durations of contrast media were 1-3 days in the patients not showing renal excretion of contrast media. The Mann-Whitney test for stay-in-colon durations demonstrated the later evacuation of contrast media in the patients with renal excretion of contrast media (p = 0.07). The review of the medical records showed that 19 patients were finally diagnosed as intestinal diseases, including Hirschsprung's disease, meconium ileum, meconium plug syndrome, and small bowel atresia or stenosis. Fisher's exact test between the presence of urinary excretion and intestinal diseases indicated a statistically significant difference (p = 0.04). Conclusion: The intestinal diseases causing bowel obstruction may increase the water-soluble contrast media's dwell time in the bowel and also increase urinary excretion.http://www.sciencedirect.com/science/article/pii/S1875957213001873contrast enemacontrast mediadiatrizoate meglumineileusinfantintestinal obstructionnewbornrenal excretionwater-soluble iodinated |
| spellingShingle | Hee Sun Kim Bo-Kyung Je Sang Hoon Cha Byung Min Choi Ki Yeol Lee Seung Hwa Lee Renal Excretion of Water-soluble Contrast Media After Enema in the Neonatal Period Pediatrics and Neonatology contrast enema contrast media diatrizoate meglumine ileus infant intestinal obstruction newborn renal excretion water-soluble iodinated |
| title | Renal Excretion of Water-soluble Contrast Media After Enema in the Neonatal Period |
| title_full | Renal Excretion of Water-soluble Contrast Media After Enema in the Neonatal Period |
| title_fullStr | Renal Excretion of Water-soluble Contrast Media After Enema in the Neonatal Period |
| title_full_unstemmed | Renal Excretion of Water-soluble Contrast Media After Enema in the Neonatal Period |
| title_short | Renal Excretion of Water-soluble Contrast Media After Enema in the Neonatal Period |
| title_sort | renal excretion of water soluble contrast media after enema in the neonatal period |
| topic | contrast enema contrast media diatrizoate meglumine ileus infant intestinal obstruction newborn renal excretion water-soluble iodinated |
| url | http://www.sciencedirect.com/science/article/pii/S1875957213001873 |
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