Effects of pelvic endometriosis and adenomyosis on ciliary beat frequency and muscular contractions in the human fallopian tube
Abstract Background Pelvic endometriosis (EM) and adenomyosis (AM) have different effects on the fallopian tube. This study aimed to assess the transport capability of the fallopian tube in women with pelvic EM or AM. Methods Twenty women with uterine leiomyoma (control group), 20 with adenomyosis w...
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| Format: | Article |
| Language: | English |
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BMC
2018-05-01
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| Series: | Reproductive Biology and Endocrinology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12958-018-0361-y |
| _version_ | 1818574248194605056 |
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| author | Wei Xia Duo Zhang Jing Ouyang Yan Liang Huiyu Zhang Zhen Huang Guiling Liang Qian Zhu Xiaoming Guan Jian Zhang |
| author_facet | Wei Xia Duo Zhang Jing Ouyang Yan Liang Huiyu Zhang Zhen Huang Guiling Liang Qian Zhu Xiaoming Guan Jian Zhang |
| author_sort | Wei Xia |
| collection | DOAJ |
| description | Abstract Background Pelvic endometriosis (EM) and adenomyosis (AM) have different effects on the fallopian tube. This study aimed to assess the transport capability of the fallopian tube in women with pelvic EM or AM. Methods Twenty women with uterine leiomyoma (control group), 20 with adenomyosis without pelvic EM (AM group) and 35 with pelvic EM without AM (EM group) were included. EM cases were further divided into the tubal EM and non-tubal EM subgroups. Ciliary beat frequency (CBF), percentage of ciliated cells, and smooth muscle contraction were measured. Results CBFs of the ampulla in EM cases were significantly lower than those of control and AM cases; CBFs of the ampulla and isthmus in tubal EM cases were significantly lower than those of the control group and non-tubal EM subgroup. In both the ampulla and isthmus segment, percentages of ciliated cells in EM patients were significantly lower than those of AM and control patients; the tubal EM subgroup showed significantly lower values than the control group and non-tubal EM subgroup. Amplitude-to-weight ratios of longitudinal muscular contractility in EM cases were significantly lower than control values; tubal EM cases showed significantly lower values than controls and the non-tubal EM subgroup. Contraction frequencies in EM cases were significantly lower than those of control and AM cases, in both longitudinal and circular muscles; tubal EM cases showed significantly lower values than controls and the non-tubal EM subgroup. Conclusion EM with tubal EM damaged transport function of the fallopian tube, to varying degrees, whereas tubal function in EM without tubal EM and in AM is not altered. |
| first_indexed | 2024-12-15T00:24:03Z |
| format | Article |
| id | doaj.art-b4cbe555f58f41e8995b05623019e719 |
| institution | Directory Open Access Journal |
| issn | 1477-7827 |
| language | English |
| last_indexed | 2024-12-15T00:24:03Z |
| publishDate | 2018-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Reproductive Biology and Endocrinology |
| spelling | doaj.art-b4cbe555f58f41e8995b05623019e7192022-12-21T22:42:13ZengBMCReproductive Biology and Endocrinology1477-78272018-05-011611710.1186/s12958-018-0361-yEffects of pelvic endometriosis and adenomyosis on ciliary beat frequency and muscular contractions in the human fallopian tubeWei Xia0Duo Zhang1Jing Ouyang2Yan Liang3Huiyu Zhang4Zhen Huang5Guiling Liang6Qian Zhu7Xiaoming Guan8Jian Zhang9Department of Obstetrics and Gynaecology, International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiaotong UniversityDepartment of Obstetrics and Gynaecology, International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiaotong UniversityDepartment of Obstetrics and Gynaecology, International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiaotong UniversityDepartment of Obstetrics and Gynaecology, International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiaotong UniversityDepartment of Obstetrics and Gynaecology, International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiaotong UniversityDepartment of Obstetrics and Gynaecology, International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiaotong UniversityDepartment of Obstetrics and Gynaecology, International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiaotong UniversityDepartment of Obstetrics and Gynaecology, International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiaotong UniversityDepartment of Obstetrics & Gynaecology, Baylor College of MedicineDepartment of Obstetrics and Gynaecology, International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiaotong UniversityAbstract Background Pelvic endometriosis (EM) and adenomyosis (AM) have different effects on the fallopian tube. This study aimed to assess the transport capability of the fallopian tube in women with pelvic EM or AM. Methods Twenty women with uterine leiomyoma (control group), 20 with adenomyosis without pelvic EM (AM group) and 35 with pelvic EM without AM (EM group) were included. EM cases were further divided into the tubal EM and non-tubal EM subgroups. Ciliary beat frequency (CBF), percentage of ciliated cells, and smooth muscle contraction were measured. Results CBFs of the ampulla in EM cases were significantly lower than those of control and AM cases; CBFs of the ampulla and isthmus in tubal EM cases were significantly lower than those of the control group and non-tubal EM subgroup. In both the ampulla and isthmus segment, percentages of ciliated cells in EM patients were significantly lower than those of AM and control patients; the tubal EM subgroup showed significantly lower values than the control group and non-tubal EM subgroup. Amplitude-to-weight ratios of longitudinal muscular contractility in EM cases were significantly lower than control values; tubal EM cases showed significantly lower values than controls and the non-tubal EM subgroup. Contraction frequencies in EM cases were significantly lower than those of control and AM cases, in both longitudinal and circular muscles; tubal EM cases showed significantly lower values than controls and the non-tubal EM subgroup. Conclusion EM with tubal EM damaged transport function of the fallopian tube, to varying degrees, whereas tubal function in EM without tubal EM and in AM is not altered.http://link.springer.com/article/10.1186/s12958-018-0361-yEndometriosisAdenomyosisCiliary beat frequency (CBF)Muscular contractionPercentage of ciliated cells |
| spellingShingle | Wei Xia Duo Zhang Jing Ouyang Yan Liang Huiyu Zhang Zhen Huang Guiling Liang Qian Zhu Xiaoming Guan Jian Zhang Effects of pelvic endometriosis and adenomyosis on ciliary beat frequency and muscular contractions in the human fallopian tube Reproductive Biology and Endocrinology Endometriosis Adenomyosis Ciliary beat frequency (CBF) Muscular contraction Percentage of ciliated cells |
| title | Effects of pelvic endometriosis and adenomyosis on ciliary beat frequency and muscular contractions in the human fallopian tube |
| title_full | Effects of pelvic endometriosis and adenomyosis on ciliary beat frequency and muscular contractions in the human fallopian tube |
| title_fullStr | Effects of pelvic endometriosis and adenomyosis on ciliary beat frequency and muscular contractions in the human fallopian tube |
| title_full_unstemmed | Effects of pelvic endometriosis and adenomyosis on ciliary beat frequency and muscular contractions in the human fallopian tube |
| title_short | Effects of pelvic endometriosis and adenomyosis on ciliary beat frequency and muscular contractions in the human fallopian tube |
| title_sort | effects of pelvic endometriosis and adenomyosis on ciliary beat frequency and muscular contractions in the human fallopian tube |
| topic | Endometriosis Adenomyosis Ciliary beat frequency (CBF) Muscular contraction Percentage of ciliated cells |
| url | http://link.springer.com/article/10.1186/s12958-018-0361-y |
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