Development of Quinazolinone Derivatives as Modulators of Virulence Factors of <i>Pseudomonas aeruginosa</i> Cystic Fibrosis Strains

Development of Quinazolinone Derivatives as Modulators of Virulence Factors of <i>Pseudomonas aeruginosa</i> Cystic Fibrosis Strains

<i>Pseudomonas aeruginosa</i> (PA), one of the ESKAPE pathogens, is an opportunistic Gram-negative bacterium responsible for nosocomial infections in humans but also for infections in patients affected by AIDS, cancer, or cystic fibrosis (CF). Treatment of PA infections in CF patients is...

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Bibliographic Details
Main Authors: Gabriele Carullo, Giovanni Di Bonaventura, Sara Rossi, Veronica Lupetti, Valeria Tudino, Simone Brogi, Stefania Butini, Giuseppe Campiani, Sandra Gemma, Arianna Pompilio
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Molecules
Subjects:
<i>Pseudomonas aeruginosa</i>
virulence factors
biofilm
quorum sensing
PqsR
cystic fibrosis
Online Access:https://www.mdpi.com/1420-3049/28/18/6535

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