Anti-Metastatic Function of Extracellular Vesicles Derived from <i>Nanog</i>-Overexpressing Melanoma

Anti-Metastatic Function of Extracellular Vesicles Derived from <i>Nanog</i>-Overexpressing Melanoma

A metastatic melanoma cell line B16-F10 (F10) was modified to a more undifferentiated state by <i>Nanog</i> overexpression. The produced cell line <i>Nanog</i><sup>+</sup>F10 showed a higher metastatic potential than F10. Instead of whole cells, the extracellular...

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Bibliographic Details
Main Authors: Tomohiro Hatakenaka, Nahoko Matsuki, Seiya Minagawa, Celine Swee May Khoo, Mikako Saito
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Current Oncology
Subjects:
melanoma
<i>Nanog</i> overexpression
extracellular vesicles
autovaccine
TGF-β1
Online Access:https://www.mdpi.com/1718-7729/29/2/88

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