Ameboma of the colon with amebic liver abscess mimicking metastatic colon cancer
Amebic colitis is common in developing countries, with its variable and non-specific symptoms. Amebomas occur rarely, resulting from the formation of annular granulation tissue, usually in the cecum and in the ascending colon. This report describes the case of a 59-year-old male who presented with a...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2009-04-01
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| Series: | Indian Journal of Pathology and Microbiology |
| Subjects: | |
| Online Access: | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2009;volume=52;issue=2;spage=228;epage=230;aulast=Fernandes |
| _version_ | 1819046391005052928 |
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| author | Fernandes Hilda D′Souza Clement Swethadri G Ramesh Naik C |
| author_facet | Fernandes Hilda D′Souza Clement Swethadri G Ramesh Naik C |
| author_sort | Fernandes Hilda |
| collection | DOAJ |
| description | Amebic colitis is common in developing countries, with its variable and non-specific symptoms. Amebomas occur rarely, resulting from the formation of annular granulation tissue, usually in the cecum and in the ascending colon. This report describes the case of a 59-year-old male who presented with abdominal pain. Radiological examination depicted concentric thickening of the cecal wall with mass formation and a cystic lesion in the liver. The endoscopy performed showed a growth in the ascending colon. Biopsy revealed extensive necrosis and inflammatory cells. The patient was referred to this hospital for surgical treatment with a provisional diagnosis of carcinoma of the colon. Peroperatively, a cecal mass was identified. However, suspected secondaries were not seen on the surface of the liver. Histological examination of the right hemicolectomy specimen revealed cecal and ascending colon amebomas. Trophozoites of <i> Entamoeba histolytica</i> were better recognized after periodic acid-Schiff staining. Treatment with Metronidazole for 2 weeks followed by diloxanide furoate for an additional 2 weeks was administered. The liver lesion resolved completely after 8 weeks. Colonic ameboma accompanied by amebic liver abscess may be misdiagnosed as metastatic colon cancer. A high index of suspicion is essential for diagnosis when dealing with colonic masses and liver lesions, especially in the tropics. |
| first_indexed | 2024-12-21T10:43:43Z |
| format | Article |
| id | doaj.art-b4d252de621a43198174ce3aa36d69c0 |
| institution | Directory Open Access Journal |
| issn | 0377-4929 |
| language | English |
| last_indexed | 2024-12-21T10:43:43Z |
| publishDate | 2009-04-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj.art-b4d252de621a43198174ce3aa36d69c02022-12-21T19:06:52ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292009-04-01522228230Ameboma of the colon with amebic liver abscess mimicking metastatic colon cancerFernandes HildaD′Souza ClementSwethadri GRamesh Naik CAmebic colitis is common in developing countries, with its variable and non-specific symptoms. Amebomas occur rarely, resulting from the formation of annular granulation tissue, usually in the cecum and in the ascending colon. This report describes the case of a 59-year-old male who presented with abdominal pain. Radiological examination depicted concentric thickening of the cecal wall with mass formation and a cystic lesion in the liver. The endoscopy performed showed a growth in the ascending colon. Biopsy revealed extensive necrosis and inflammatory cells. The patient was referred to this hospital for surgical treatment with a provisional diagnosis of carcinoma of the colon. Peroperatively, a cecal mass was identified. However, suspected secondaries were not seen on the surface of the liver. Histological examination of the right hemicolectomy specimen revealed cecal and ascending colon amebomas. Trophozoites of <i> Entamoeba histolytica</i> were better recognized after periodic acid-Schiff staining. Treatment with Metronidazole for 2 weeks followed by diloxanide furoate for an additional 2 weeks was administered. The liver lesion resolved completely after 8 weeks. Colonic ameboma accompanied by amebic liver abscess may be misdiagnosed as metastatic colon cancer. A high index of suspicion is essential for diagnosis when dealing with colonic masses and liver lesions, especially in the tropics.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2009;volume=52;issue=2;spage=228;epage=230;aulast=FernandesAmebomacecummetastatic cancer |
| spellingShingle | Fernandes Hilda D′Souza Clement Swethadri G Ramesh Naik C Ameboma of the colon with amebic liver abscess mimicking metastatic colon cancer Indian Journal of Pathology and Microbiology Ameboma cecum metastatic cancer |
| title | Ameboma of the colon with amebic liver abscess mimicking metastatic colon cancer |
| title_full | Ameboma of the colon with amebic liver abscess mimicking metastatic colon cancer |
| title_fullStr | Ameboma of the colon with amebic liver abscess mimicking metastatic colon cancer |
| title_full_unstemmed | Ameboma of the colon with amebic liver abscess mimicking metastatic colon cancer |
| title_short | Ameboma of the colon with amebic liver abscess mimicking metastatic colon cancer |
| title_sort | ameboma of the colon with amebic liver abscess mimicking metastatic colon cancer |
| topic | Ameboma cecum metastatic cancer |
| url | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2009;volume=52;issue=2;spage=228;epage=230;aulast=Fernandes |
| work_keys_str_mv | AT fernandeshilda amebomaofthecolonwithamebicliverabscessmimickingmetastaticcoloncancer AT dx2032souzaclement amebomaofthecolonwithamebicliverabscessmimickingmetastaticcoloncancer AT swethadrig amebomaofthecolonwithamebicliverabscessmimickingmetastaticcoloncancer AT rameshnaikc amebomaofthecolonwithamebicliverabscessmimickingmetastaticcoloncancer |