A Comparative Study of Propofol and Isoflurane Anaesthesia using Butorphanol in Neurosurgery
Propofol and isoflurane have well proven roles as intravenous and inhalational anaesthetics respectively in neurosurgery. We conducted this study to know the outcome using butorphanol as an intraoperative analgesic. Sixty craniotomy patients randomly divided into two groups of 30 each were included...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2009-01-01
|
| Series: | Indian Journal of Anaesthesia |
| Subjects: | |
| Online Access: | http://www.ijaweb.org/article.asp?issn=0019-5049;year=2009;volume=53;issue=3;spage=324;epage=329;aulast=Mishra |
| _version_ | 1818494124332941312 |
|---|---|
| author | L D Mishra N Rajkumar S N Singh R K Dubey G Yadav |
| author_facet | L D Mishra N Rajkumar S N Singh R K Dubey G Yadav |
| author_sort | L D Mishra |
| collection | DOAJ |
| description | Propofol and isoflurane have well proven roles as intravenous and inhalational anaesthetics respectively in neurosurgery. We conducted this study to know the outcome using butorphanol as an intraoperative analgesic. Sixty craniotomy patients randomly divided into two groups of 30 each were included in this study. Group A patients were induced and maintained with propofol. Group B patients were induced with thiopentone and maintained with isoflurane. All patients were administered 30µg.kg -1 butorphanol intravenously 10 minutes before induction of anaesthesia, fol-lowed by slow injection of 30µg.kg -1 midazolam. All were assessed for sedation, respiratory insufficiency, postopera-tive nausea and vomiting (PONV) and other side effects in the recovery room. We found no difference in demo-graphic parameters between the groups. The fall in HR was maintained in the post induction / intubation period and throughout the intraoperative period in Group A, unlike Group B patients in whom it rose significantly following intubation. Butorphanol was found to be a safe intraoperative analgesic in neurosurgical patients. In addition, it was associated with statistically better haemodynamics and earlier recovery when used with propofol as compared to thiopentone-isoflurane anaesthesia. |
| first_indexed | 2024-12-10T18:02:30Z |
| format | Article |
| id | doaj.art-b4d2b5ba4969494387132ceabfd9f265 |
| institution | Directory Open Access Journal |
| issn | 0019-5049 |
| language | English |
| last_indexed | 2024-12-10T18:02:30Z |
| publishDate | 2009-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Anaesthesia |
| spelling | doaj.art-b4d2b5ba4969494387132ceabfd9f2652022-12-22T01:38:43ZengWolters Kluwer Medknow PublicationsIndian Journal of Anaesthesia0019-50492009-01-01533324329A Comparative Study of Propofol and Isoflurane Anaesthesia using Butorphanol in NeurosurgeryL D MishraN RajkumarS N SinghR K DubeyG YadavPropofol and isoflurane have well proven roles as intravenous and inhalational anaesthetics respectively in neurosurgery. We conducted this study to know the outcome using butorphanol as an intraoperative analgesic. Sixty craniotomy patients randomly divided into two groups of 30 each were included in this study. Group A patients were induced and maintained with propofol. Group B patients were induced with thiopentone and maintained with isoflurane. All patients were administered 30µg.kg -1 butorphanol intravenously 10 minutes before induction of anaesthesia, fol-lowed by slow injection of 30µg.kg -1 midazolam. All were assessed for sedation, respiratory insufficiency, postopera-tive nausea and vomiting (PONV) and other side effects in the recovery room. We found no difference in demo-graphic parameters between the groups. The fall in HR was maintained in the post induction / intubation period and throughout the intraoperative period in Group A, unlike Group B patients in whom it rose significantly following intubation. Butorphanol was found to be a safe intraoperative analgesic in neurosurgical patients. In addition, it was associated with statistically better haemodynamics and earlier recovery when used with propofol as compared to thiopentone-isoflurane anaesthesia.http://www.ijaweb.org/article.asp?issn=0019-5049;year=2009;volume=53;issue=3;spage=324;epage=329;aulast=MishraCraniotomyPropofolIsofluraneButorphanolHaemodynamicsExtubation timeRecovery of consciousness |
| spellingShingle | L D Mishra N Rajkumar S N Singh R K Dubey G Yadav A Comparative Study of Propofol and Isoflurane Anaesthesia using Butorphanol in Neurosurgery Indian Journal of Anaesthesia Craniotomy Propofol Isoflurane Butorphanol Haemodynamics Extubation time Recovery of consciousness |
| title | A Comparative Study of Propofol and Isoflurane Anaesthesia using Butorphanol in Neurosurgery |
| title_full | A Comparative Study of Propofol and Isoflurane Anaesthesia using Butorphanol in Neurosurgery |
| title_fullStr | A Comparative Study of Propofol and Isoflurane Anaesthesia using Butorphanol in Neurosurgery |
| title_full_unstemmed | A Comparative Study of Propofol and Isoflurane Anaesthesia using Butorphanol in Neurosurgery |
| title_short | A Comparative Study of Propofol and Isoflurane Anaesthesia using Butorphanol in Neurosurgery |
| title_sort | comparative study of propofol and isoflurane anaesthesia using butorphanol in neurosurgery |
| topic | Craniotomy Propofol Isoflurane Butorphanol Haemodynamics Extubation time Recovery of consciousness |
| url | http://www.ijaweb.org/article.asp?issn=0019-5049;year=2009;volume=53;issue=3;spage=324;epage=329;aulast=Mishra |
| work_keys_str_mv | AT ldmishra acomparativestudyofpropofolandisofluraneanaesthesiausingbutorphanolinneurosurgery AT nrajkumar acomparativestudyofpropofolandisofluraneanaesthesiausingbutorphanolinneurosurgery AT snsingh acomparativestudyofpropofolandisofluraneanaesthesiausingbutorphanolinneurosurgery AT rkdubey acomparativestudyofpropofolandisofluraneanaesthesiausingbutorphanolinneurosurgery AT gyadav acomparativestudyofpropofolandisofluraneanaesthesiausingbutorphanolinneurosurgery AT ldmishra comparativestudyofpropofolandisofluraneanaesthesiausingbutorphanolinneurosurgery AT nrajkumar comparativestudyofpropofolandisofluraneanaesthesiausingbutorphanolinneurosurgery AT snsingh comparativestudyofpropofolandisofluraneanaesthesiausingbutorphanolinneurosurgery AT rkdubey comparativestudyofpropofolandisofluraneanaesthesiausingbutorphanolinneurosurgery AT gyadav comparativestudyofpropofolandisofluraneanaesthesiausingbutorphanolinneurosurgery |