Engineering constructed of high selectivity dexamethasone aptamer based on truncation and mutation technology

Various biosensors based on aptamers are currently the most popular rapid detection approaches, but the performance of these sensors is closely related to the affinity of aptamers. In this work, a strategy for constructed high-affinity aptamer was proposed. By truncating the bases flanking the 59 nt...

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Hlavní autoři: Yadi Qin, Yanan Qin, Hayilati Bubiajiaer, Fengxia Chen, Jun Yao, Minwei Zhang
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2022-09-01
Edice:Frontiers in Bioengineering and Biotechnology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fbioe.2022.994711/full