Genistein Reduces the Risk of Local Mammary Cancer Recurrence and Ameliorates Alterations in the Gut Microbiota in the Offspring of Obese Dams

Genistein Reduces the Risk of Local Mammary Cancer Recurrence and Ameliorates Alterations in the Gut Microbiota in the Offspring of Obese Dams

The risk of recurrence of estrogen receptor-positive breast cancer remains constant, even 20 years after diagnosis. Recurrence may be more likely in patients pre-programmed for it already in the womb, such as in the daughters born to obese mothers. Maternal obesity persistently alters offspring’s gu...

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Bibliographic Details
Main Authors: Fabia de Oliveira Andrade, Fang Liu, Xiyuan Zhang, Mariana Papaleo Rosim, Caroline Dani, Idalia Cruz, Thomas T. Y. Wang, William Helferich, Robert W. Li, Leena Hilakivi-Clarke
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Nutrients
Subjects:
breast cancer
tamoxifen therapy
antiestrogen resistance
genistein
gut microbiota
tumor immune genes
Online Access:https://www.mdpi.com/2072-6643/13/1/201

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