Oral Mucosal Manifestations Associated With PCR Positivity in Patients With COVID-19
Introduction: To date various oral manifestations in patients with coronavirus disease 2019 (COVID-19) have been reported. Objectives: In the present study, we investigated the relationship between Polymerase Chain Reaction (PCR) positivity and oral signs in patients with suspected COVID-19. Me...
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| Format: | Article |
| Language: | English |
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Mattioli1885
2024-01-01
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| Series: | Dermatology Practical & Conceptual |
| Subjects: | |
| Online Access: | https://dpcj.org/index.php/dpc/article/view/3486 |
| _version_ | 1797324077703102464 |
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| author | Nurcan Metin Türkan Tuğba Yıldız Çağrı Turan |
| author_facet | Nurcan Metin Türkan Tuğba Yıldız Çağrı Turan |
| author_sort | Nurcan Metin |
| collection | DOAJ |
| description |
Introduction: To date various oral manifestations in patients with coronavirus disease 2019 (COVID-19) have been reported.
Objectives: In the present study, we investigated the relationship between Polymerase Chain Reaction (PCR) positivity and oral signs in patients with suspected COVID-19.
Methods: A total of 383 patients who presented to the emergency department for the first time with any symptoms associated with COVID-19 were included in the study. Oral examinations were performed and the findings, PCR status, and thorax computerized tomography (CT) reports were recorded.
Results: Oral mucosa was involved in 246 (64.2%) patients. 175 (78,4%) of patients with COVID-19 confirmed the diagnosis with PCR test or CT results had oral manifestation. Dry mouth, microvesicles on the tonsils or pharynx, and petechiae in the oropharynx were significantly higher in patients with positive PCR tests (P = 0.001, P < 0.001, P < 0.001, respectively). The ratio of intact oral mucosa was statistically significantly higher in patients with negative PCR tests compared to those with positive PCR tests (P < 0.001). Microvesicles on the tonsils or pharynx were most associated with PCR positivity in patients without lung involvement (P < 0.001). Dry mouth, erythema of the tonsils and pharynx, petechiae in the oropharynx, and primary/secondary herpes infection are more related to PCR positivity in patients without lung involvement (P < 0.05). Lung involvement in patients with PCR positivity is related to only cheilitis (P = 0.034).
Conclusions: Our study revealed that especially microvesicles, petechiae, erythema on the tonsils or pharynx, and some other oral lesions such as dry mouth, oral aphthae, and primary/secondary herpes infection are associated with PCR positivity.
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| first_indexed | 2024-03-08T05:45:03Z |
| format | Article |
| id | doaj.art-b4d7039b8303496882817daec6ef6447 |
| institution | Directory Open Access Journal |
| issn | 2160-9381 |
| language | English |
| last_indexed | 2024-03-08T05:45:03Z |
| publishDate | 2024-01-01 |
| publisher | Mattioli1885 |
| record_format | Article |
| series | Dermatology Practical & Conceptual |
| spelling | doaj.art-b4d7039b8303496882817daec6ef64472024-02-05T13:15:37ZengMattioli1885Dermatology Practical & Conceptual2160-93812024-01-0114110.5826/dpc.1401a45Oral Mucosal Manifestations Associated With PCR Positivity in Patients With COVID-19Nurcan Metin0Türkan Tuğba Yıldız1Çağrı Turan2Department of Dermatology and Venereology, the Republic of Turkey, Health Sciences University Erzurum Regional Training and Research Hospital, Erzurum, TurkeyDepartment of Dermatology and Venereology, the Republic of Turkey, Health Sciences University Erzurum Regional Training and Research Hospital, Erzurum, TurkeyDepartment of Dermatology and Venereology, the Republic of Turkey, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey Introduction: To date various oral manifestations in patients with coronavirus disease 2019 (COVID-19) have been reported. Objectives: In the present study, we investigated the relationship between Polymerase Chain Reaction (PCR) positivity and oral signs in patients with suspected COVID-19. Methods: A total of 383 patients who presented to the emergency department for the first time with any symptoms associated with COVID-19 were included in the study. Oral examinations were performed and the findings, PCR status, and thorax computerized tomography (CT) reports were recorded. Results: Oral mucosa was involved in 246 (64.2%) patients. 175 (78,4%) of patients with COVID-19 confirmed the diagnosis with PCR test or CT results had oral manifestation. Dry mouth, microvesicles on the tonsils or pharynx, and petechiae in the oropharynx were significantly higher in patients with positive PCR tests (P = 0.001, P < 0.001, P < 0.001, respectively). The ratio of intact oral mucosa was statistically significantly higher in patients with negative PCR tests compared to those with positive PCR tests (P < 0.001). Microvesicles on the tonsils or pharynx were most associated with PCR positivity in patients without lung involvement (P < 0.001). Dry mouth, erythema of the tonsils and pharynx, petechiae in the oropharynx, and primary/secondary herpes infection are more related to PCR positivity in patients without lung involvement (P < 0.05). Lung involvement in patients with PCR positivity is related to only cheilitis (P = 0.034). Conclusions: Our study revealed that especially microvesicles, petechiae, erythema on the tonsils or pharynx, and some other oral lesions such as dry mouth, oral aphthae, and primary/secondary herpes infection are associated with PCR positivity. https://dpcj.org/index.php/dpc/article/view/3486COVID-19PCR testoral mucosaManifestationsmicrovesiclespetechiae |
| spellingShingle | Nurcan Metin Türkan Tuğba Yıldız Çağrı Turan Oral Mucosal Manifestations Associated With PCR Positivity in Patients With COVID-19 Dermatology Practical & Conceptual COVID-19 PCR test oral mucosa Manifestations microvesicles petechiae |
| title | Oral Mucosal Manifestations Associated With PCR Positivity in Patients With COVID-19 |
| title_full | Oral Mucosal Manifestations Associated With PCR Positivity in Patients With COVID-19 |
| title_fullStr | Oral Mucosal Manifestations Associated With PCR Positivity in Patients With COVID-19 |
| title_full_unstemmed | Oral Mucosal Manifestations Associated With PCR Positivity in Patients With COVID-19 |
| title_short | Oral Mucosal Manifestations Associated With PCR Positivity in Patients With COVID-19 |
| title_sort | oral mucosal manifestations associated with pcr positivity in patients with covid 19 |
| topic | COVID-19 PCR test oral mucosa Manifestations microvesicles petechiae |
| url | https://dpcj.org/index.php/dpc/article/view/3486 |
| work_keys_str_mv | AT nurcanmetin oralmucosalmanifestationsassociatedwithpcrpositivityinpatientswithcovid19 AT turkantugbayıldız oralmucosalmanifestationsassociatedwithpcrpositivityinpatientswithcovid19 AT cagrıturan oralmucosalmanifestationsassociatedwithpcrpositivityinpatientswithcovid19 |