Rapidly progressing malignant phyllodes tumor of the prostate with normal prostate-specific antigen levels: A case report
Malignant phyllodes tumor of the prostate is a very rare entity. Here, we describe a 51-year-old patient with a malignant phyllodes tumor of the prostate with a poor prognosis and normal prostate-specific antigen levels. Digital rectal examination revealed a hard, nodular mass in the prostate, and m...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Indian Journal of Pathology and Microbiology |
| Subjects: | |
| Online Access: | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2020;volume=63;issue=5;spage=50;epage=52;aulast=Zhang |
| _version_ | 1811214661887983616 |
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| author | Xiaorong Zhang Jiali Hu Xiao Xu Lin Cheng |
| author_facet | Xiaorong Zhang Jiali Hu Xiao Xu Lin Cheng |
| author_sort | Xiaorong Zhang |
| collection | DOAJ |
| description | Malignant phyllodes tumor of the prostate is a very rare entity. Here, we describe a 51-year-old patient with a malignant phyllodes tumor of the prostate with a poor prognosis and normal prostate-specific antigen levels. Digital rectal examination revealed a hard, nodular mass in the prostate, and magnetic resonance imaging exhibited a cystic mass measuring 8.7 cm × 7.0 cm × 6.7 cm. Immunohistochemical staining showed that the epithelial components were positive for CK8/18 and cytokeratin AE1/AE3; the atypical stromal cells were positive for CD34 and vimentin. Histological analysis resulted in a diagnosis of malignant phyllodes tumor of the prostate. Radical surgery was the treatment of choice. However, tumor recurrence was identified 6 months after the surgery, and the patient died 10 months after the surgery. |
| first_indexed | 2024-04-12T06:07:30Z |
| format | Article |
| id | doaj.art-b4db819615194950b35943dbef41ac72 |
| institution | Directory Open Access Journal |
| issn | 0377-4929 |
| language | English |
| last_indexed | 2024-04-12T06:07:30Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj.art-b4db819615194950b35943dbef41ac722022-12-22T03:44:48ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292020-01-01635505210.4103/IJPM.IJPM_427_18Rapidly progressing malignant phyllodes tumor of the prostate with normal prostate-specific antigen levels: A case reportXiaorong ZhangJiali HuXiao XuLin ChengMalignant phyllodes tumor of the prostate is a very rare entity. Here, we describe a 51-year-old patient with a malignant phyllodes tumor of the prostate with a poor prognosis and normal prostate-specific antigen levels. Digital rectal examination revealed a hard, nodular mass in the prostate, and magnetic resonance imaging exhibited a cystic mass measuring 8.7 cm × 7.0 cm × 6.7 cm. Immunohistochemical staining showed that the epithelial components were positive for CK8/18 and cytokeratin AE1/AE3; the atypical stromal cells were positive for CD34 and vimentin. Histological analysis resulted in a diagnosis of malignant phyllodes tumor of the prostate. Radical surgery was the treatment of choice. However, tumor recurrence was identified 6 months after the surgery, and the patient died 10 months after the surgery.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2020;volume=63;issue=5;spage=50;epage=52;aulast=Zhangimmunohistochemical analysismalignant phyllodes tumorprostateprostate-specific antigen |
| spellingShingle | Xiaorong Zhang Jiali Hu Xiao Xu Lin Cheng Rapidly progressing malignant phyllodes tumor of the prostate with normal prostate-specific antigen levels: A case report Indian Journal of Pathology and Microbiology immunohistochemical analysis malignant phyllodes tumor prostate prostate-specific antigen |
| title | Rapidly progressing malignant phyllodes tumor of the prostate with normal prostate-specific antigen levels: A case report |
| title_full | Rapidly progressing malignant phyllodes tumor of the prostate with normal prostate-specific antigen levels: A case report |
| title_fullStr | Rapidly progressing malignant phyllodes tumor of the prostate with normal prostate-specific antigen levels: A case report |
| title_full_unstemmed | Rapidly progressing malignant phyllodes tumor of the prostate with normal prostate-specific antigen levels: A case report |
| title_short | Rapidly progressing malignant phyllodes tumor of the prostate with normal prostate-specific antigen levels: A case report |
| title_sort | rapidly progressing malignant phyllodes tumor of the prostate with normal prostate specific antigen levels a case report |
| topic | immunohistochemical analysis malignant phyllodes tumor prostate prostate-specific antigen |
| url | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2020;volume=63;issue=5;spage=50;epage=52;aulast=Zhang |
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