PSEN1 c.1292C<A Variant and Early-Onset Alzheimer’s Disease: A Scoping Review

Alzheimer’s disease (AD) is the most common cause of dementia, characterized by progressive loss of cognitive function, with β-amyloid plaques and neurofibrillary tangles being its major pathological findings. Although the disease mainly affects the elderly, c. 5–10% of the cases are due to PSEN1, P...

Full description

Bibliographic Details
Main Authors: Maribel Orozco-Barajas, Yulisa Oropeza-Ruvalcaba, Alejandro A. Canales-Aguirre, Victor J. Sánchez-González
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.860529/full