Schlafen 12 Slows TNBC Tumor Growth, Induces Luminal Markers, and Predicts Favorable Survival

Schlafen 12 Slows TNBC Tumor Growth, Induces Luminal Markers, and Predicts Favorable Survival

The Schlafen 12 (SLFN12) protein regulates triple-negative breast cancer (TNBC) growth, differentiation, and proliferation. SLFN12 mRNA expression strongly correlates with TNBC patient survival. We sought to explore SLFN12 overexpression effects on in vivo human TNBC tumor xenograft growth and perfo...

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Bibliographic Details
Main Authors: Sandeep K. Singhal, Sarmad Al-Marsoummi, Emilie E. Vomhof-DeKrey, Bo Lauckner, Trysten Beyer, Marc D. Basson
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cancers
Subjects:
prognostic predictor
personalized medicine
xenograft
RNA sequencing
race
Online Access:https://www.mdpi.com/2072-6694/15/2/402

Internet

https://www.mdpi.com/2072-6694/15/2/402

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