MicroRNA Profile, Putative Diagnostic Biomarkers and RNA-Based Therapies in the Inherited Lipid Storage Disease Niemann-Pick Type C

MicroRNA Profile, Putative Diagnostic Biomarkers and RNA-Based Therapies in the Inherited Lipid Storage Disease Niemann-Pick Type C

Lipids are essential for cellular function and are tightly controlled at the transcriptional and post-transcriptional levels. Dysregulation of these pathways is associated with vascular diseases, diabetes, cancer, and several inherited metabolic disorders. MicroRNAs (miRNAs), in particular, are a fa...

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Autors principals: Marisa Encarnação, Hugo David, Maria Francisca Coutinho, Luciana Moreira, Sandra Alves
Format: Article
Idioma:English
Publicat: MDPI AG 2023-09-01
Col·lecció:Biomedicines
Matèries:
microRNA
lipid storage disorders
metabolism
cholesterol trafficking
biomarkers
Niemann-Pick type C
Accés en línia:https://www.mdpi.com/2227-9059/11/10/2615

Internet

https://www.mdpi.com/2227-9059/11/10/2615

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