EFFECT OF ETHYLMETHYLHYDROXYPYRIDINE MALATE ON THE ABSOLUTE NUMBERS OF ERYTHROBLASTIC ISLETS IN RATS EXPOSED TO SULFUR-CONTANING GAS AT DIFFERENT STAGES OF POSTNATAL ONTOGENESIS
Objective. To study the effect of the protective agent ethylmethylhydroxypyridine malate on the numbers of erythroblastic islets in rats exposed to sulfur-containing gases. Materials and methods. Natural sulfur-containing gas mixtures from the Astrakhan gas-condensate field were used to model the ga...
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Format: | Article |
Language: | Russian |
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IRBIS LLC
2017-08-01
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Series: | Акушерство, гинекология и репродукция |
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Online Access: | https://www.gynecology.su/jour/article/view/408 |
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author | O. A. Ovsyannikova D. V. Karpeeva M. D. Osipenko |
author_facet | O. A. Ovsyannikova D. V. Karpeeva M. D. Osipenko |
author_sort | O. A. Ovsyannikova |
collection | DOAJ |
description | Objective. To study the effect of the protective agent ethylmethylhydroxypyridine malate on the numbers of erythroblastic islets in rats exposed to sulfur-containing gases. Materials and methods. Natural sulfur-containing gas mixtures from the Astrakhan gas-condensate field were used to model the gas-polluted environment. Male rats of various ages simulated different stages of postnatal human ontogenesis. Results. The obtained results indicate that at all stages of ontogenesis ethylmethylhydroxypyridine malate protected erythroblastic islets from intoxication by gaseous sulfur pollutants and led to partial normalization of proliferation and maturation of eryth rob lasts. Conclusion. The protective action of ethylmethylhydroxypyridine malate may be used for neutralizing the biological damage caused by toxic air pollutants at different stages of ontogenesis. |
first_indexed | 2024-04-10T04:01:57Z |
format | Article |
id | doaj.art-b4ebd012129f42948fee1bd5a082cfc8 |
institution | Directory Open Access Journal |
issn | 2313-7347 2500-3194 |
language | Russian |
last_indexed | 2024-04-10T04:01:57Z |
publishDate | 2017-08-01 |
publisher | IRBIS LLC |
record_format | Article |
series | Акушерство, гинекология и репродукция |
spelling | doaj.art-b4ebd012129f42948fee1bd5a082cfc82023-03-13T07:09:49ZrusIRBIS LLCАкушерство, гинекология и репродукция2313-73472500-31942017-08-01112232810.17749/2313-7347.2017.11.2.023-028389EFFECT OF ETHYLMETHYLHYDROXYPYRIDINE MALATE ON THE ABSOLUTE NUMBERS OF ERYTHROBLASTIC ISLETS IN RATS EXPOSED TO SULFUR-CONTANING GAS AT DIFFERENT STAGES OF POSTNATAL ONTOGENESISO. A. Ovsyannikova0D. V. Karpeeva1M. D. Osipenko2Astrakhan State Medical University, Health Ministry of Russian FederationAstrakhan State Medical University, Health Ministry of Russian FederationAstrakhan State Medical University, Health Ministry of Russian FederationObjective. To study the effect of the protective agent ethylmethylhydroxypyridine malate on the numbers of erythroblastic islets in rats exposed to sulfur-containing gases. Materials and methods. Natural sulfur-containing gas mixtures from the Astrakhan gas-condensate field were used to model the gas-polluted environment. Male rats of various ages simulated different stages of postnatal human ontogenesis. Results. The obtained results indicate that at all stages of ontogenesis ethylmethylhydroxypyridine malate protected erythroblastic islets from intoxication by gaseous sulfur pollutants and led to partial normalization of proliferation and maturation of eryth rob lasts. Conclusion. The protective action of ethylmethylhydroxypyridine malate may be used for neutralizing the biological damage caused by toxic air pollutants at different stages of ontogenesis.https://www.gynecology.su/jour/article/view/408erythropoiesissulfur dioxideethylmethylhydroxypyridine malateratsstages of ontogeny |
spellingShingle | O. A. Ovsyannikova D. V. Karpeeva M. D. Osipenko EFFECT OF ETHYLMETHYLHYDROXYPYRIDINE MALATE ON THE ABSOLUTE NUMBERS OF ERYTHROBLASTIC ISLETS IN RATS EXPOSED TO SULFUR-CONTANING GAS AT DIFFERENT STAGES OF POSTNATAL ONTOGENESIS Акушерство, гинекология и репродукция erythropoiesis sulfur dioxide ethylmethylhydroxypyridine malate rats stages of ontogeny |
title | EFFECT OF ETHYLMETHYLHYDROXYPYRIDINE MALATE ON THE ABSOLUTE NUMBERS OF ERYTHROBLASTIC ISLETS IN RATS EXPOSED TO SULFUR-CONTANING GAS AT DIFFERENT STAGES OF POSTNATAL ONTOGENESIS |
title_full | EFFECT OF ETHYLMETHYLHYDROXYPYRIDINE MALATE ON THE ABSOLUTE NUMBERS OF ERYTHROBLASTIC ISLETS IN RATS EXPOSED TO SULFUR-CONTANING GAS AT DIFFERENT STAGES OF POSTNATAL ONTOGENESIS |
title_fullStr | EFFECT OF ETHYLMETHYLHYDROXYPYRIDINE MALATE ON THE ABSOLUTE NUMBERS OF ERYTHROBLASTIC ISLETS IN RATS EXPOSED TO SULFUR-CONTANING GAS AT DIFFERENT STAGES OF POSTNATAL ONTOGENESIS |
title_full_unstemmed | EFFECT OF ETHYLMETHYLHYDROXYPYRIDINE MALATE ON THE ABSOLUTE NUMBERS OF ERYTHROBLASTIC ISLETS IN RATS EXPOSED TO SULFUR-CONTANING GAS AT DIFFERENT STAGES OF POSTNATAL ONTOGENESIS |
title_short | EFFECT OF ETHYLMETHYLHYDROXYPYRIDINE MALATE ON THE ABSOLUTE NUMBERS OF ERYTHROBLASTIC ISLETS IN RATS EXPOSED TO SULFUR-CONTANING GAS AT DIFFERENT STAGES OF POSTNATAL ONTOGENESIS |
title_sort | effect of ethylmethylhydroxypyridine malate on the absolute numbers of erythroblastic islets in rats exposed to sulfur contaning gas at different stages of postnatal ontogenesis |
topic | erythropoiesis sulfur dioxide ethylmethylhydroxypyridine malate rats stages of ontogeny |
url | https://www.gynecology.su/jour/article/view/408 |
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