Muver, a computational framework for accurately calling accumulated mutations

Muver, a computational framework for accurately calling accumulated mutations

Abstract Background Identification of mutations from next-generation sequencing data typically requires a balance between sensitivity and accuracy. This is particularly true of DNA insertions and deletions (indels), that can impart significant phenotypic consequences on cells but are harder to call...

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Bibliographic Details
Main Authors: Adam B. Burkholder, Scott A. Lujan, Christopher A. Lavender, Sara A. Grimm, Thomas A. Kunkel, David C. Fargo
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Genomics
Subjects:
DNA-seq
Indel
Mutation
Mutation accumulation
Mutation rate
Online Access:http://link.springer.com/article/10.1186/s12864-018-4753-3

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http://link.springer.com/article/10.1186/s12864-018-4753-3

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