Morphometric evaluation of features of remodeling of chondrocites of joint surfaces of temporomandibular joint of experimental animals in hyperglycemia
<p>Aim: to study morphometrically the peculiarities of remodeling of chondrocytes of the articular surfaces of the temporomandibular joint in hyperglycemia.</p><p>Materials and methods: Quantitative morphological methods were used to study diameters of chondrocytes and their nuclei...
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| Format: | Article |
| Language: | English |
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Kazimierz Wielki University
2021-06-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/czasopisma/index.php/JEHS/article/view/34531 |
| _version_ | 1818730015099977728 |
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| author | Mykhailo Hnatiuk Lesia Rubas |
| author_facet | Mykhailo Hnatiuk Lesia Rubas |
| author_sort | Mykhailo Hnatiuk |
| collection | DOAJ |
| description | <p>Aim: to study morphometrically the peculiarities of remodeling of chondrocytes of the articular surfaces of the temporomandibular joint in hyperglycemia.</p><p>Materials and methods: Quantitative morphological methods were used to study diameters of chondrocytes and their nuclei, nuclear-cytoplasmic relationship in these cells, relative volume of damaged chondrocytes, intercellular-chondrocytic relationship in mature chondrocytes of the articular surfaces of the temporomandibular joint of 45 laboratory mature white male rats with simulated diabetes.</p><p>Results: A comprehensive analysis of the morphometric parameters presented in the article showed that they did not differ in the articular surfaces of the temporal fossa and mandibular head of the intact temporomandibular joint. The expressed structural changes of chondrocytes were revealed at a monthly and a two-month diabetic arthropathy of this joint.</p><p>Conclusions: Proceeded studies and obtained results suggest that prolonged hyperglycemia leads to diabetic arthropathy of the TMJ, which is characterized by atrophy of chondrocytes, violation of nuclear-cytoplasmic relationships, an increase in the relative volume of damaged chondrocytes and volume of intercellular substance. The detected changes in quantitative morphological parameters depended on the duration of hyperglycemia and dominated in the cartilaginous tissue of the articular surface of the mandibular head.</p> |
| first_indexed | 2024-12-17T22:55:03Z |
| format | Article |
| id | doaj.art-b4ef241ee5bd4a72b2b784c0a29b890f |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-12-17T22:55:03Z |
| publishDate | 2021-06-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-b4ef241ee5bd4a72b2b784c0a29b890f2022-12-21T21:29:34ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062021-06-0111613714210.12775/JEHS.2021.11.06.01427481Morphometric evaluation of features of remodeling of chondrocites of joint surfaces of temporomandibular joint of experimental animals in hyperglycemiaMykhailo Hnatiuk0Lesia Rubas1I.Ya. Horbachevsky Ternopil National Medical UniversityI.Ya. Horbachevsky Ternopil National Medical University<p>Aim: to study morphometrically the peculiarities of remodeling of chondrocytes of the articular surfaces of the temporomandibular joint in hyperglycemia.</p><p>Materials and methods: Quantitative morphological methods were used to study diameters of chondrocytes and their nuclei, nuclear-cytoplasmic relationship in these cells, relative volume of damaged chondrocytes, intercellular-chondrocytic relationship in mature chondrocytes of the articular surfaces of the temporomandibular joint of 45 laboratory mature white male rats with simulated diabetes.</p><p>Results: A comprehensive analysis of the morphometric parameters presented in the article showed that they did not differ in the articular surfaces of the temporal fossa and mandibular head of the intact temporomandibular joint. The expressed structural changes of chondrocytes were revealed at a monthly and a two-month diabetic arthropathy of this joint.</p><p>Conclusions: Proceeded studies and obtained results suggest that prolonged hyperglycemia leads to diabetic arthropathy of the TMJ, which is characterized by atrophy of chondrocytes, violation of nuclear-cytoplasmic relationships, an increase in the relative volume of damaged chondrocytes and volume of intercellular substance. The detected changes in quantitative morphological parameters depended on the duration of hyperglycemia and dominated in the cartilaginous tissue of the articular surface of the mandibular head.</p>https://apcz.umk.pl/czasopisma/index.php/JEHS/article/view/34531hondrocytestemporomandibular jointhyperglycemiacartilaginous tissue |
| spellingShingle | Mykhailo Hnatiuk Lesia Rubas Morphometric evaluation of features of remodeling of chondrocites of joint surfaces of temporomandibular joint of experimental animals in hyperglycemia Journal of Education, Health and Sport hondrocytes temporomandibular joint hyperglycemia cartilaginous tissue |
| title | Morphometric evaluation of features of remodeling of chondrocites of joint surfaces of temporomandibular joint of experimental animals in hyperglycemia |
| title_full | Morphometric evaluation of features of remodeling of chondrocites of joint surfaces of temporomandibular joint of experimental animals in hyperglycemia |
| title_fullStr | Morphometric evaluation of features of remodeling of chondrocites of joint surfaces of temporomandibular joint of experimental animals in hyperglycemia |
| title_full_unstemmed | Morphometric evaluation of features of remodeling of chondrocites of joint surfaces of temporomandibular joint of experimental animals in hyperglycemia |
| title_short | Morphometric evaluation of features of remodeling of chondrocites of joint surfaces of temporomandibular joint of experimental animals in hyperglycemia |
| title_sort | morphometric evaluation of features of remodeling of chondrocites of joint surfaces of temporomandibular joint of experimental animals in hyperglycemia |
| topic | hondrocytes temporomandibular joint hyperglycemia cartilaginous tissue |
| url | https://apcz.umk.pl/czasopisma/index.php/JEHS/article/view/34531 |
| work_keys_str_mv | AT mykhailohnatiuk morphometricevaluationoffeaturesofremodelingofchondrocitesofjointsurfacesoftemporomandibularjointofexperimentalanimalsinhyperglycemia AT lesiarubas morphometricevaluationoffeaturesofremodelingofchondrocitesofjointsurfacesoftemporomandibularjointofexperimentalanimalsinhyperglycemia |