Wenjing Zhitong recipe exhibits potential anti-primary dysmenorrhea properties by inhibiting COX2 and PKC signaling pathway in rats induced by estradiol benzoate and oxytocin

Wenjing Zhitong recipe exhibits potential anti-primary dysmenorrhea properties by inhibiting COX2 and PKC signaling pathway in rats induced by estradiol benzoate and oxytocin

Objective: To explore the effect and mechanism of action of the Wenjing Zhitong recipe (WZR) in primary dysmenorrhea (PD) treatment. Methods: Uterine contractions were induced by estradiol benzoate and oxytocin in a PD model and WZR was administrated. The rate of change in uterine contractility and...

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Bibliographic Details
Main Authors: Jialin Li, Xiaoyao Liu, Mei Jiang, Yantong Xu, Chunguo Wang, Yujie Hu, Song Yang, Jian Gao, Weiling Wang, Ting Wang
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Journal of Traditional Chinese Medical Sciences
Subjects:
Wenjing zhitong recipe
Primary dysmenorrhea
Network pharmacology
PGF2α
PKC system
Online Access:http://www.sciencedirect.com/science/article/pii/S209575482300039X

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