<it>PNPLA 3</it> I148M genetic variant associates with insulin resistance and baseline viral load in HCV genotype 2 but not in genotype 3 infection

<it>PNPLA 3</it> I148M genetic variant associates with insulin resistance and baseline viral load in HCV genotype 2 but not in genotype 3 infection

<p>Abstract</p> <p>Background</p> <p>Hepatic steatosis in HCV patients has been postulated as a risk factor associated with a higher frequency of fibrosis and cirrhosis. A single genetic variant, <it>PNPLA3</it> I148M, has been widely associated with increas...

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Bibliographic Details
Main Authors: Rembeck Karolina, Maglio Cristina, Lagging Martin, Christensen Peer, Färkkilä Martti, Langeland Nina, Buhl Mads, Pedersen Court, Mørch Kristine, Norkrans Gunnar, Hellstrand Kristoffer, Lindh Magnus, Pirazzi Carlo, Burza Maria, Romeo Stefano, Westin Johan
Format: Article
Language:English
Published: BMC 2012-09-01
Series:BMC Medical Genetics
Subjects:
Hepatitis C
<it>PNPLA 3</it>
Insulin resistance
Viral load
Online Access:http://www.biomedcentral.com/1471-2350/13/82

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