Genomics of experimental adaptation of Staphylococcus aureus to a natural combination of insect antimicrobial peptides

Genomics of experimental adaptation of Staphylococcus aureus to a natural combination of insect antimicrobial peptides

Abstract Antimicrobial peptides (AMP) are highly conserved immune effectors across the tree of life and are employed as combinations. In the beetle Tenebrio molitor, a defensin and a coleoptericin are highly expressed in vivo after inoculation with S. aureus. The defensin displays strong in vitro ac...

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Bibliographic Details
Main Authors: Olga Makarova, Paul Johnston, Alexandro Rodriguez-Rojas, Baydaa El Shazely, Javier Moreno Morales, Jens Rolff
Format: Article
Language:English
Published: Nature Portfolio 2018-10-01
Series:Scientific Reports
Subjects:
Antimicrobial Peptides (AMPs)
Abundant AMPs
Resistance Development
Resistance Cost
Pexiganan
Online Access:https://doi.org/10.1038/s41598-018-33593-7

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