Inhibition of extracellular signal-regulated kinase pathway suppresses tracheal stenosis in a novel mouse model.
Tracheal stenosis is a refractory and recurrent disease induced by excessive cell proliferation within the restricted tracheal space. We investigated the role of extracellular signal-regulated kinase (ERK), which mediates a broad range of intracellular signal transduction processes in tracheal steno...
Main Authors: | Akari Kimura, Koji Araki, Yasushi Satoh, Sachiyo Mogi, Kazuko Fujitani, Takaomi Kurioka, Shogo Endo, Akihiro Shiotani, Taku Yamashita |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0256127 |
Similar Items
-
Transient Conductive Hearing Loss Regulates Cross-Modal VGLUT Expression in the Cochlear Nucleus of C57BL/6 Mice
by: Takaomi Kurioka, et al.
Published: (2020-04-01) -
Decreasing auditory input induces neurogenesis impairment in the hippocampus
by: Takaomi Kurioka, et al.
Published: (2021-01-01) -
Gene therapy of c-myc suppressor FUSE-binding protein-interacting repressor by Sendai virus delivery prevents tracheal stenosis.
by: Daisuke Mizokami, et al.
Published: (2015-01-01) -
Protective Effect of Neurotrophic Agent T-817MA Against Inner Ear Barotrauma in the Guinea Pig
by: Hitoshi Maekawa, et al.
Published: (2011-01-01) -
Effects of the Conductive Component of Hearing Loss on Speech Discrimination Ability
by: Takaomi Kurioka, et al.
Published: (2020-04-01)