Evaluation of the Difference of L-selectin, Tumor Necrosis Factor- and Sialic Acid Concentration in Dairy Cows with Subclinical Ketosis and without Subclinical Ketosis
Ketosis is a major disease related with negative energy balance and immune suppression in dairy cows. The objective of this study was to examine the differences in β-hydroxybutyrate (BHBA), L-selectin, glucose, tumor necrosis factor-α (TNF-α), non-esterified fatty acids (NEFA), and sialic acid (SA)...
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| Format: | Article |
| Language: | English |
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University of Agriculture, Faisalabad
2013-04-01
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| Series: | Pakistan Veterinary Journal |
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| Online Access: | http://pvj.com.pk/pdf-files/33_2/225-228.pdf |
| _version_ | 1819053048584994816 |
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| author | Z. G. Zhang1,§, J. D. Xue§2,§, R. F. Gao3,§, J.Y. Liu1,§, J. G. Wang3, C. Y. Yao2, Y. Liu2, X. W. Li3, X. B. Li3, G. W. Liu3 and Z. Wang3,* |
| author_facet | Z. G. Zhang1,§, J. D. Xue§2,§, R. F. Gao3,§, J.Y. Liu1,§, J. G. Wang3, C. Y. Yao2, Y. Liu2, X. W. Li3, X. B. Li3, G. W. Liu3 and Z. Wang3,* |
| author_sort | Z. G. Zhang1,§, J. D. Xue§2,§, R. F. Gao3,§, J.Y. Liu1,§, J. G. Wang3, C. Y. Yao2, Y. Liu2, X. W. Li3, X. B. Li3, G. W. Liu3 and Z. Wang3,* |
| collection | DOAJ |
| description | Ketosis is a major disease related with negative energy balance and immune suppression in dairy cows. The objective of this study was to examine the differences in β-hydroxybutyrate (BHBA), L-selectin, glucose, tumor necrosis factor-α (TNF-α), non-esterified fatty acids (NEFA), and sialic acid (SA) concentrations in serum in healthy dairy cows and those with subclinical ketosis during the early lactation period. The blood from 20 healthy cows and 20 subclinically affected cows were sampled. All the cows were within the first 2 months of lactation. Serum concentrations of the various aforementioned factors were measured using a number of different methods. The results demonstrated that in cows affected by subclinical ketosis, NEFA concentrations were significantly higher, and glucose and L-selectin concentrations were significantly lower than healthy cows. There was no significant difference in serum SA and TNF-α of dairy cows with subclinical ketosis compared to the control cows. The decrease in concentration of serum L-selectin may be related to immune suppression. |
| first_indexed | 2024-12-21T12:29:32Z |
| format | Article |
| id | doaj.art-b4fca18ace764e3ba1b853b5ce67947d |
| institution | Directory Open Access Journal |
| issn | 0253-8318 |
| language | English |
| last_indexed | 2024-12-21T12:29:32Z |
| publishDate | 2013-04-01 |
| publisher | University of Agriculture, Faisalabad |
| record_format | Article |
| series | Pakistan Veterinary Journal |
| spelling | doaj.art-b4fca18ace764e3ba1b853b5ce67947d2022-12-21T19:04:05ZengUniversity of Agriculture, FaisalabadPakistan Veterinary Journal0253-83182013-04-01332225228Evaluation of the Difference of L-selectin, Tumor Necrosis Factor- and Sialic Acid Concentration in Dairy Cows with Subclinical Ketosis and without Subclinical KetosisZ. G. Zhang1,§, J. D. Xue§2,§, R. F. Gao3,§, J.Y. Liu1,§, J. G. Wang3, C. Y. Yao2, Y. Liu2, X. W. Li3, X. B. Li3, G. W. Liu3 and Z. Wang3,*Ketosis is a major disease related with negative energy balance and immune suppression in dairy cows. The objective of this study was to examine the differences in β-hydroxybutyrate (BHBA), L-selectin, glucose, tumor necrosis factor-α (TNF-α), non-esterified fatty acids (NEFA), and sialic acid (SA) concentrations in serum in healthy dairy cows and those with subclinical ketosis during the early lactation period. The blood from 20 healthy cows and 20 subclinically affected cows were sampled. All the cows were within the first 2 months of lactation. Serum concentrations of the various aforementioned factors were measured using a number of different methods. The results demonstrated that in cows affected by subclinical ketosis, NEFA concentrations were significantly higher, and glucose and L-selectin concentrations were significantly lower than healthy cows. There was no significant difference in serum SA and TNF-α of dairy cows with subclinical ketosis compared to the control cows. The decrease in concentration of serum L-selectin may be related to immune suppression.http://pvj.com.pk/pdf-files/33_2/225-228.pdfImmune suppressionL-selectinSubclinical ketosisSialic acidTNF- |
| spellingShingle | Z. G. Zhang1,§, J. D. Xue§2,§, R. F. Gao3,§, J.Y. Liu1,§, J. G. Wang3, C. Y. Yao2, Y. Liu2, X. W. Li3, X. B. Li3, G. W. Liu3 and Z. Wang3,* Evaluation of the Difference of L-selectin, Tumor Necrosis Factor- and Sialic Acid Concentration in Dairy Cows with Subclinical Ketosis and without Subclinical Ketosis Pakistan Veterinary Journal Immune suppression L-selectin Subclinical ketosis Sialic acid TNF- |
| title | Evaluation of the Difference of L-selectin, Tumor Necrosis Factor- and Sialic Acid Concentration in Dairy Cows with Subclinical Ketosis and without Subclinical Ketosis |
| title_full | Evaluation of the Difference of L-selectin, Tumor Necrosis Factor- and Sialic Acid Concentration in Dairy Cows with Subclinical Ketosis and without Subclinical Ketosis |
| title_fullStr | Evaluation of the Difference of L-selectin, Tumor Necrosis Factor- and Sialic Acid Concentration in Dairy Cows with Subclinical Ketosis and without Subclinical Ketosis |
| title_full_unstemmed | Evaluation of the Difference of L-selectin, Tumor Necrosis Factor- and Sialic Acid Concentration in Dairy Cows with Subclinical Ketosis and without Subclinical Ketosis |
| title_short | Evaluation of the Difference of L-selectin, Tumor Necrosis Factor- and Sialic Acid Concentration in Dairy Cows with Subclinical Ketosis and without Subclinical Ketosis |
| title_sort | evaluation of the difference of l selectin tumor necrosis factor and sialic acid concentration in dairy cows with subclinical ketosis and without subclinical ketosis |
| topic | Immune suppression L-selectin Subclinical ketosis Sialic acid TNF- |
| url | http://pvj.com.pk/pdf-files/33_2/225-228.pdf |
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