An immunometabolic patch facilitates mesenchymal stromal/stem cell therapy for myocardial infarction through a macrophage‐dependent mechanism

An immunometabolic patch facilitates mesenchymal stromal/stem cell therapy for myocardial infarction through a macrophage‐dependent mechanism

Abstract Mesenchymal stromal/stem cells (MSCs) have emerged as a promising approach against myocardial infarction. Due to hostile hyperinflammation, however, poor retention of transplanted cells seriously impedes their clinical applications. Proinflammatory M1 macrophages, which rely on glycolysis a...

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Bibliographic Details
Main Authors: Weizhang Xiao, Ming Chen, Wenjing Zhou, Liang Ding, Ziying Yang, Lianbo Shao, Jingjing Li, Weiqian Chen, Zhenya Shen
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:Bioengineering & Translational Medicine
Subjects:
glycolysis
immunometabolism
macrophage
mesenchymal stromal/stem cells
myocardial infarction
patch
Online Access:https://doi.org/10.1002/btm2.10471

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