Cytotoxic and mutagenic effects of the food additive tartrazine on eukaryotic cells

Cytotoxic and mutagenic effects of the food additive tartrazine on eukaryotic cells

Abstract Background Among the food additives used in the food industry, food dyes are considered the most toxic. For instance, tartrazine (TRZ) is a food colorant commercially available with conflicting data regarding its cytotoxic, genotoxic, and mutagenic effects. Therefore, this study aimed to ev...

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Main Authors: Jailson Rodrigues dos Santos, Larissa de Sousa Soares, Bruno Moreira Soares, Marlene de Gomes Farias, Victor Alves de Oliveira, Natan Antônio Batista de Sousa, Helber Alves Negreiros, Felipe Cavalcanti Carneiro da Silva, Ana Paula Peron, Ana Carolina Landim Pacheco, Márcia Maria Mendes Marques, Juan Carlos Ramos Gonçalves, Raquel Carvalho Montenegro, Muhammad Torequl Islam, Javad Sharifi-Rad, Mohammad S. Mubarak, Ana Amélia Carvalho de Melo Cavalcante, João Marcelo de Castro e Sousa
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Pharmacology and Toxicology
Subjects:
Carcinogenesis
Tartrazine
Cell line
Allium cepa
Artemia salina
Saccharomyces cerevisiae
Online Access:https://doi.org/10.1186/s40360-022-00638-7

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