Comparison of Equations Estimating Resting Metabolic Rate in Older Adults with Type 2 Diabetes
Measuring resting metabolic rate (RMR) is time-consuming and expensive, and thus various equations for estimating RMR have been developed. This study’s objective was to compare five equations in elderly people with type 2 diabetes (T2DM). RMR was measured in 90 older adults (≥65 years) with T2DM (me...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-04-01
|
| Series: | Journal of Clinical Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0383/10/8/1644 |
| _version_ | 1797537945308102656 |
|---|---|
| author | Assaf Buch Jonathan Diener Naftali Stern Amir Rubin Ofer Kis Yael Sofer Mariana Yaron Yona Greenman Roy Eldor Sigal Eilat-Adar |
| author_facet | Assaf Buch Jonathan Diener Naftali Stern Amir Rubin Ofer Kis Yael Sofer Mariana Yaron Yona Greenman Roy Eldor Sigal Eilat-Adar |
| author_sort | Assaf Buch |
| collection | DOAJ |
| description | Measuring resting metabolic rate (RMR) is time-consuming and expensive, and thus various equations for estimating RMR have been developed. This study’s objective was to compare five equations in elderly people with type 2 diabetes (T2DM). RMR was measured in 90 older adults (≥65 years) with T2DM (mean body mass index (BMI) of 31.5 kg/m<sup>2</sup>), using indirect calorimetry. Results were compared to four frequently used equations (those of Cunningham, Harris and Benedict, and Gougeon developed for young adults with T2DM, and that of Lührmann, which was developed for the elderly), in addition to a new equation developed recently at the Academic College at Wingate (Nachmani) for overweight individuals. Estimation accuracy was defined as the percentage of subjects with calculated RMR within ±10% of measured RMR. Measured RMR was significantly underestimated by all equations. The equations of Nachmani and Lührmann had the best estimation accuracy: 71.4% in males and 50.9% in females. Skeletal muscle mass, fat mass, hemoglobin A1c (HbA1c), and the use of insulin explained 70.6% of the variability in measured RMR. RMR in elderly participants with T2DM was higher than that calculated using existing equations. The most accurate equations for this specific population were those developed for obesity or the elderly. Unbalanced T2DM may increase caloric demands in the elderly. It is recommended to adjust the RMR equations used for the target population. |
| first_indexed | 2024-03-10T12:23:28Z |
| format | Article |
| id | doaj.art-b4fed3ab9bf741d4ac448c13ceb89aed |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T12:23:28Z |
| publishDate | 2021-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-b4fed3ab9bf741d4ac448c13ceb89aed2023-11-21T15:16:06ZengMDPI AGJournal of Clinical Medicine2077-03832021-04-01108164410.3390/jcm10081644Comparison of Equations Estimating Resting Metabolic Rate in Older Adults with Type 2 DiabetesAssaf Buch0Jonathan Diener1Naftali Stern2Amir Rubin3Ofer Kis4Yael Sofer5Mariana Yaron6Yona Greenman7Roy Eldor8Sigal Eilat-Adar9Institute of Endocrinology, Metabolism and Hypertension, Tel Aviv Sourasky Medical Center, Tel-Aviv 64239, IsraelInstitute of Sports and Sports Science, Karlsruhe Institute of Technology, 76131 Karlsruhe, GermanyThe Sagol Center for Epigenetics of Metabolism and Aging, Tel Aviv Sourasky Medical Center, Tel-Aviv 64239, IsraelThe Academic College at Wingate, Wingate Institute, Netanya 42902, IsraelInstitute of Endocrinology, Metabolism and Hypertension, Tel Aviv Sourasky Medical Center, Tel-Aviv 64239, IsraelInstitute of Endocrinology, Metabolism and Hypertension, Tel Aviv Sourasky Medical Center, Tel-Aviv 64239, IsraelInstitute of Endocrinology, Metabolism and Hypertension, Tel Aviv Sourasky Medical Center, Tel-Aviv 64239, IsraelInstitute of Endocrinology, Metabolism and Hypertension, Tel Aviv Sourasky Medical Center, Tel-Aviv 64239, IsraelInstitute of Endocrinology, Metabolism and Hypertension, Tel Aviv Sourasky Medical Center, Tel-Aviv 64239, IsraelThe Academic College at Wingate, Wingate Institute, Netanya 42902, IsraelMeasuring resting metabolic rate (RMR) is time-consuming and expensive, and thus various equations for estimating RMR have been developed. This study’s objective was to compare five equations in elderly people with type 2 diabetes (T2DM). RMR was measured in 90 older adults (≥65 years) with T2DM (mean body mass index (BMI) of 31.5 kg/m<sup>2</sup>), using indirect calorimetry. Results were compared to four frequently used equations (those of Cunningham, Harris and Benedict, and Gougeon developed for young adults with T2DM, and that of Lührmann, which was developed for the elderly), in addition to a new equation developed recently at the Academic College at Wingate (Nachmani) for overweight individuals. Estimation accuracy was defined as the percentage of subjects with calculated RMR within ±10% of measured RMR. Measured RMR was significantly underestimated by all equations. The equations of Nachmani and Lührmann had the best estimation accuracy: 71.4% in males and 50.9% in females. Skeletal muscle mass, fat mass, hemoglobin A1c (HbA1c), and the use of insulin explained 70.6% of the variability in measured RMR. RMR in elderly participants with T2DM was higher than that calculated using existing equations. The most accurate equations for this specific population were those developed for obesity or the elderly. Unbalanced T2DM may increase caloric demands in the elderly. It is recommended to adjust the RMR equations used for the target population.https://www.mdpi.com/2077-0383/10/8/1644resting metabolic rateelderlytype 2 diabetesobesitypredictive equationsenergy expenditure |
| spellingShingle | Assaf Buch Jonathan Diener Naftali Stern Amir Rubin Ofer Kis Yael Sofer Mariana Yaron Yona Greenman Roy Eldor Sigal Eilat-Adar Comparison of Equations Estimating Resting Metabolic Rate in Older Adults with Type 2 Diabetes Journal of Clinical Medicine resting metabolic rate elderly type 2 diabetes obesity predictive equations energy expenditure |
| title | Comparison of Equations Estimating Resting Metabolic Rate in Older Adults with Type 2 Diabetes |
| title_full | Comparison of Equations Estimating Resting Metabolic Rate in Older Adults with Type 2 Diabetes |
| title_fullStr | Comparison of Equations Estimating Resting Metabolic Rate in Older Adults with Type 2 Diabetes |
| title_full_unstemmed | Comparison of Equations Estimating Resting Metabolic Rate in Older Adults with Type 2 Diabetes |
| title_short | Comparison of Equations Estimating Resting Metabolic Rate in Older Adults with Type 2 Diabetes |
| title_sort | comparison of equations estimating resting metabolic rate in older adults with type 2 diabetes |
| topic | resting metabolic rate elderly type 2 diabetes obesity predictive equations energy expenditure |
| url | https://www.mdpi.com/2077-0383/10/8/1644 |
| work_keys_str_mv | AT assafbuch comparisonofequationsestimatingrestingmetabolicrateinolderadultswithtype2diabetes AT jonathandiener comparisonofequationsestimatingrestingmetabolicrateinolderadultswithtype2diabetes AT naftalistern comparisonofequationsestimatingrestingmetabolicrateinolderadultswithtype2diabetes AT amirrubin comparisonofequationsestimatingrestingmetabolicrateinolderadultswithtype2diabetes AT oferkis comparisonofequationsestimatingrestingmetabolicrateinolderadultswithtype2diabetes AT yaelsofer comparisonofequationsestimatingrestingmetabolicrateinolderadultswithtype2diabetes AT marianayaron comparisonofequationsestimatingrestingmetabolicrateinolderadultswithtype2diabetes AT yonagreenman comparisonofequationsestimatingrestingmetabolicrateinolderadultswithtype2diabetes AT royeldor comparisonofequationsestimatingrestingmetabolicrateinolderadultswithtype2diabetes AT sigaleilatadar comparisonofequationsestimatingrestingmetabolicrateinolderadultswithtype2diabetes |