Phospholipase C δ-4 overexpression upregulates ErbB1/2 expression, Erk signaling pathway, and proliferation in MCF-7 cells

Phospholipase C δ-4 overexpression upregulates ErbB1/2 expression, Erk signaling pathway, and proliferation in MCF-7 cells

<p>Abstract</p> <p>Background</p> <p>The expression of the rodent phosphoinositide-specific phospholipase C δ-4 (PLCδ4) has been found to be elevated upon mitogenic stimulation and expression analysis have linked the upregulation of PLCδ4 expression with rapid prolifera...

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Bibliographic Details
Main Authors: Morris Valerie, Coon Mike, Ball Alexey, Brewer Jim, Tompkins Chris, Leung David W, Waggoner David, Singer Jack W
Format: Article
Language:English
Published: BMC 2004-05-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/3/1/15

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