SYNTHESIS AND CATECHOLASE ACTIVITY OF Cu(II) AND Fe(III) COMPLEXES OF 4-METHYL-2-((PIPERIDIN-1-YL)METHYL)PHENOL
This study is aimed at evaluating the impact of N- and S- bonding modes of thiocyanate substituent on catecholase activity as its presence in the coordination sphere of the metal complex can either reduce catecholase activity or otherwise. 4-Methyl-2-((piperidin-1- yl)methyl) phenol - the Mannic...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Alma Mater Publishing House "Vasile Alecsandri" University of Bacau
2020-12-01
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| Series: | Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry |
| Subjects: | |
| Online Access: | http://pubs.ub.ro/?pg=revues&rev=cscc6&num=202004&vol=4&aid=5186 |
| _version_ | 1798028766963826688 |
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| author | AYOWOLE O. AYENI GARETH M. WATKINS 1 |
| author_facet | AYOWOLE O. AYENI GARETH M. WATKINS 1 |
| author_sort | AYOWOLE O. AYENI |
| collection | DOAJ |
| description | This study is aimed at evaluating the impact of
N- and S- bonding modes of thiocyanate substituent on catecholase activity
as its presence in the coordination sphere of the metal complex can either
reduce catecholase activity or otherwise. 4-Methyl-2-((piperidin-1-
yl)methyl) phenol - the Mannich base and its synthesized metal complexes
were characterized by various spectroscopic techniques including NMR, IR,
and UV-Vis spectroscopy. Turnover rates obtained from the Cu(II) and
Fe(III) complexes ranged between 6.02 - 22.72 h-1 with the thiocyanate
mode in the Fe(III) complex leading to increased catecholase activity. |
| first_indexed | 2024-04-11T19:13:40Z |
| format | Article |
| id | doaj.art-b5084fa2fd094148ac74882b97a8efb4 |
| institution | Directory Open Access Journal |
| issn | 1582-540X 1582-540X |
| language | English |
| last_indexed | 2024-04-11T19:13:40Z |
| publishDate | 2020-12-01 |
| publisher | Alma Mater Publishing House "Vasile Alecsandri" University of Bacau |
| record_format | Article |
| series | Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry |
| spelling | doaj.art-b5084fa2fd094148ac74882b97a8efb42022-12-22T04:07:32ZengAlma Mater Publishing House "Vasile Alecsandri" University of BacauScientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry1582-540X1582-540X2020-12-01214453462SYNTHESIS AND CATECHOLASE ACTIVITY OF Cu(II) AND Fe(III) COMPLEXES OF 4-METHYL-2-((PIPERIDIN-1-YL)METHYL)PHENOLAYOWOLE O. AYENI0GARETH M. WATKINS 111. Rhodes University, Department of Chemistry, Grahamstown 6139, South Africa 2. Obafemi Awolowo University, Department of Chemistry, Ile-Ife 220005, Nigeria1. Rhodes University, Department of Chemistry, Grahamstown 6139, South Africa This study is aimed at evaluating the impact of N- and S- bonding modes of thiocyanate substituent on catecholase activity as its presence in the coordination sphere of the metal complex can either reduce catecholase activity or otherwise. 4-Methyl-2-((piperidin-1- yl)methyl) phenol - the Mannich base and its synthesized metal complexes were characterized by various spectroscopic techniques including NMR, IR, and UV-Vis spectroscopy. Turnover rates obtained from the Cu(II) and Fe(III) complexes ranged between 6.02 - 22.72 h-1 with the thiocyanate mode in the Fe(III) complex leading to increased catecholase activity.http://pubs.ub.ro/?pg=revues&rev=cscc6&num=202004&vol=4&aid=5186aminomethylationmonobaseoxidationpiperidinequinone |
| spellingShingle | AYOWOLE O. AYENI GARETH M. WATKINS 1 SYNTHESIS AND CATECHOLASE ACTIVITY OF Cu(II) AND Fe(III) COMPLEXES OF 4-METHYL-2-((PIPERIDIN-1-YL)METHYL)PHENOL Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry aminomethylation monobase oxidation piperidine quinone |
| title | SYNTHESIS AND CATECHOLASE ACTIVITY OF Cu(II) AND Fe(III) COMPLEXES OF 4-METHYL-2-((PIPERIDIN-1-YL)METHYL)PHENOL |
| title_full | SYNTHESIS AND CATECHOLASE ACTIVITY OF Cu(II) AND Fe(III) COMPLEXES OF 4-METHYL-2-((PIPERIDIN-1-YL)METHYL)PHENOL |
| title_fullStr | SYNTHESIS AND CATECHOLASE ACTIVITY OF Cu(II) AND Fe(III) COMPLEXES OF 4-METHYL-2-((PIPERIDIN-1-YL)METHYL)PHENOL |
| title_full_unstemmed | SYNTHESIS AND CATECHOLASE ACTIVITY OF Cu(II) AND Fe(III) COMPLEXES OF 4-METHYL-2-((PIPERIDIN-1-YL)METHYL)PHENOL |
| title_short | SYNTHESIS AND CATECHOLASE ACTIVITY OF Cu(II) AND Fe(III) COMPLEXES OF 4-METHYL-2-((PIPERIDIN-1-YL)METHYL)PHENOL |
| title_sort | synthesis and catecholase activity of cu ii and fe iii complexes of 4 methyl 2 piperidin 1 yl methyl phenol |
| topic | aminomethylation monobase oxidation piperidine quinone |
| url | http://pubs.ub.ro/?pg=revues&rev=cscc6&num=202004&vol=4&aid=5186 |
| work_keys_str_mv | AT ayowoleoayeni synthesisandcatecholaseactivityofcuiiandfeiiicomplexesof4methyl2piperidin1ylmethylphenol AT garethmwatkins1 synthesisandcatecholaseactivityofcuiiandfeiiicomplexesof4methyl2piperidin1ylmethylphenol |