Diphtheria Outbreak among Children in 2017–2018: a Single Centre Study in Indonesia

Diphtheria is an acute infectious disease caused by the bacterium Corynebacterium diphtheriae. Accurate and prompt diagnosis is essential for effective case management, predicting disease prognosis, preventing complications, and ensuring cost-effective medical intervention. This study aimed to asses...

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Main Authors: Nur Aliza, Siti Maemun, Dedet Hidayati Yoenoes, Mega Oktariena Syafendra, Desrinawati Muhammad Amin, Yeni Afrina, Atika Rahmawani, Dara Tyas Putri Aryanto, Farida Murtiani
Format: Article
Language:English
Published: Universitas Islam Bandung 2023-08-01
Series:Global Medical & Health Communication
Subjects:
Online Access:https://ejournal.unisba.ac.id/index.php/gmhc/article/view/10951
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author Nur Aliza
Siti Maemun
Dedet Hidayati Yoenoes
Mega Oktariena Syafendra
Desrinawati Muhammad Amin
Yeni Afrina
Atika Rahmawani
Dara Tyas Putri Aryanto
Farida Murtiani
author_facet Nur Aliza
Siti Maemun
Dedet Hidayati Yoenoes
Mega Oktariena Syafendra
Desrinawati Muhammad Amin
Yeni Afrina
Atika Rahmawani
Dara Tyas Putri Aryanto
Farida Murtiani
author_sort Nur Aliza
collection DOAJ
description Diphtheria is an acute infectious disease caused by the bacterium Corynebacterium diphtheriae. Accurate and prompt diagnosis is essential for effective case management, predicting disease prognosis, preventing complications, and ensuring cost-effective medical intervention. This study aimed to assess the variety of clinical symptoms exhibited by pediatric diphtheria cases during an outbreak. An observational cross-sectional study was conducted using data from the medical records of pediatric diphtheria cases at Sulianti Saroso Infectious Disease Hospital from November 1, 2017, to February 28, 2018. The study involved 202 cases, and statistical analysis was performed using the chi-square test. Out of the 202 cases, 58.4% were male. Age distribution was <1 year: 7.4%, 1–2 years: 3.5%, >2–5 years: 24.8%, >5–12 years: 45.5%, and >12 years: 18.8%. Anamnestic findings revealed the presence of fever in 88.1% of patients, pain upon swallowing in 73.3%, and cough in 55.4%. Clinically, every patient exhibited pseudomembrane formations. Other findings included bilateral tonsillar involvement in 53%, lymphadenopathy in 40.1%, bullneck in 17.8%, and snoring in 7.9%. Four significant variables were associated with the diphtheria diagnosis: fever, snoring, bullneck, and snoring (p<0.05) respectively. Clinical signs and symptoms are pivotal in establishing a diphtheria diagnosis in pediatric cases.
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spelling doaj.art-b508a1d7b39e451db6a24758b1b3bcd32024-01-18T06:46:43ZengUniversitas Islam BandungGlobal Medical & Health Communication2301-91232460-54412023-08-0111210.29313/gmhc.v11i2.109514894Diphtheria Outbreak among Children in 2017–2018: a Single Centre Study in IndonesiaNur Aliza0Siti Maemun1Dedet Hidayati Yoenoes2Mega Oktariena Syafendra3Desrinawati Muhammad Amin4Yeni Afrina5Atika Rahmawani6Dara Tyas Putri Aryanto7Farida Murtiani8Sulianti Saroso Infectious Disease Hospital, Jakarta1. Sulianti Saroso Infectious Disease Hospital, Jakarta 2. Department of Public Health, Universitas Respati Indonesia, Jakarta 3. Indonesia Epidemiological Association (PAEI), JakartaSulianti Saroso Infectious Disease Hospital, JakartaSulianti Saroso Infectious Disease Hospital, JakartaSulianti Saroso Infectious Disease Hospital, JakartaSulianti Saroso Infectious Disease Hospital, JakartaSulianti Saroso Infectious Disease Hospital, JakartaSulianti Saroso Infectious Disease Hospital, JakartaSulianti Saroso Infectious Disease Hospital, JakartaDiphtheria is an acute infectious disease caused by the bacterium Corynebacterium diphtheriae. Accurate and prompt diagnosis is essential for effective case management, predicting disease prognosis, preventing complications, and ensuring cost-effective medical intervention. This study aimed to assess the variety of clinical symptoms exhibited by pediatric diphtheria cases during an outbreak. An observational cross-sectional study was conducted using data from the medical records of pediatric diphtheria cases at Sulianti Saroso Infectious Disease Hospital from November 1, 2017, to February 28, 2018. The study involved 202 cases, and statistical analysis was performed using the chi-square test. Out of the 202 cases, 58.4% were male. Age distribution was <1 year: 7.4%, 1–2 years: 3.5%, >2–5 years: 24.8%, >5–12 years: 45.5%, and >12 years: 18.8%. Anamnestic findings revealed the presence of fever in 88.1% of patients, pain upon swallowing in 73.3%, and cough in 55.4%. Clinically, every patient exhibited pseudomembrane formations. Other findings included bilateral tonsillar involvement in 53%, lymphadenopathy in 40.1%, bullneck in 17.8%, and snoring in 7.9%. Four significant variables were associated with the diphtheria diagnosis: fever, snoring, bullneck, and snoring (p<0.05) respectively. Clinical signs and symptoms are pivotal in establishing a diphtheria diagnosis in pediatric cases.https://ejournal.unisba.ac.id/index.php/gmhc/article/view/10951childrendiphtheriaoutbreak
spellingShingle Nur Aliza
Siti Maemun
Dedet Hidayati Yoenoes
Mega Oktariena Syafendra
Desrinawati Muhammad Amin
Yeni Afrina
Atika Rahmawani
Dara Tyas Putri Aryanto
Farida Murtiani
Diphtheria Outbreak among Children in 2017–2018: a Single Centre Study in Indonesia
Global Medical & Health Communication
children
diphtheria
outbreak
title Diphtheria Outbreak among Children in 2017–2018: a Single Centre Study in Indonesia
title_full Diphtheria Outbreak among Children in 2017–2018: a Single Centre Study in Indonesia
title_fullStr Diphtheria Outbreak among Children in 2017–2018: a Single Centre Study in Indonesia
title_full_unstemmed Diphtheria Outbreak among Children in 2017–2018: a Single Centre Study in Indonesia
title_short Diphtheria Outbreak among Children in 2017–2018: a Single Centre Study in Indonesia
title_sort diphtheria outbreak among children in 2017 2018 a single centre study in indonesia
topic children
diphtheria
outbreak
url https://ejournal.unisba.ac.id/index.php/gmhc/article/view/10951
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